L862-0562 Screening compound: N-(2,3-dihydro-1H-inden-1-yl)-2-[5,7-dioxo-2-(piperidin-1-yl)-6-(prop-2-en-1-yl)-4H,5H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-4-yl]acetamide

L862-0562 Screening compound: N-(2,3-dihydro-1H-inden-1-yl)-2-[5,7-dioxo-2-(piperidin-1-yl)-6-(prop-2-en-1-yl)-4H,5H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-4-yl]acetamide
L862-0562 Screening compound: N-(2,3-dihydro-1H-inden-1-yl)-2-[5,7-dioxo-2-(piperidin-1-yl)-6-(prop-2-en-1-yl)-4H,5H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-4-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L862-0562
N-(2,3-dihydro-1H-inden-1-yl)-2-[5,7-dioxo-2-(piperidin-1-yl)-6-(prop-2-en-1-yl)-4H,5H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-4-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L862-0562

Molecular Formula

C24H27N5O3S (C24 H27 N5 O3 S)

Compound Name

N-(2,3-dihydro-1H-inden-1-yl)-2-[5,7-dioxo-2-(piperidin-1-yl)-6-(prop-2-en-1-yl)-4H,5H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-4-yl]acetamide

IUPAC name

N-(23-dihydro-1H-inden-1-yl)-2-[57-dioxo-2-(piperidin-1-yl)-6-(prop-2-en-1-yl)-4H5H6H7H-[13]thiazolo[45-d]pyrimidin-4-yl]acetamide

SMILES

C=CCN(C(c1c(N2CC(NC(CC3)c4c3cccc4)=O)nc(N3CCCCC3)s1)=O)C2=O

InChI

InChI=1S/C24H27N5O3S/c1-2-12-28-22(31)20-21(26-23(33-20)27-13-6-3-7-14-27)29(24(28)32)15-19(30)25-18-11-10-16-8-4-5-9-17(16)18/h2,4-5,8-9,18H,1,3,6-7,10-15H2,(H,25,30)/t18-/m0/s1

InChI Key

FMXFDVARTWMTJA-SFHVURJKSA-N

MDL Number (MFCD)

MFCD27481871

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

465.58

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.159

Distribution Coefficient, logD

4.159

Water Solubility, LogSw

-4.06

Polar Surface Area

70.754

Acid Dissociation Constant (pKa)

12.90

Base Dissociation Constant (pKb)

0.21

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

41.70

L862-0562 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • GPCR
  • Others
Mechanism of action:
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with L862-0562 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L862-0562?
Check Price and Availability of L862-0562, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L862-0562 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L862-0562
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L862-0562
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L862-0562 available by request