L865-0055 Screening compound: N-(9-ethyl-9H-carbazol-3-yl)-1-{7-oxo-6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-2-yl}piperidine-4-carboxamide

L865-0055 Screening compound: N-(9-ethyl-9H-carbazol-3-yl)-1-{7-oxo-6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-2-yl}piperidine-4-carboxamide
L865-0055 Screening compound: N-(9-ethyl-9H-carbazol-3-yl)-1-{7-oxo-6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-2-yl}piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L865-0055
N-(9-ethyl-9H-carbazol-3-yl)-1-{7-oxo-6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-2-yl}piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L865-0055

Molecular Formula

C25H24N6O2S (C25 H24 N6 O2 S)

Compound Name

N-(9-ethyl-9H-carbazol-3-yl)-1-{7-oxo-6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-2-yl}piperidine-4-carboxamide

IUPAC name

N-(9-ethyl-9H-carbazol-3-yl)-1-{7-oxo-6H7H-[13]thiazolo[45-d]pyrimidin-2-yl}piperidine-4-carboxamide

SMILES

CCn1c(ccc(NC(C(CC2)CCN2c2nc(N=CNC3=O)c3s2)=O)c2)c2c2c1cccc2

InChI

InChI=1S/C25H24N6O2S/c1-2-31-19-6-4-3-5-17(19)18-13-16(7-8-20(18)31)28-23(32)15-9-11-30(12-10-15)25-29-22-21(34-25)24(33)27-14-26-22/h3-8,13-15H,2,9-12H2,1H3,(H,28,32)(H,26,27,33)

InChI Key

GCKDOMFDAHIHEX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27482445

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

472.57

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.104

Distribution Coefficient, logD

4.101

Water Solubility, LogSw

-4.06

Polar Surface Area

73.574

Acid Dissociation Constant (pKa)

9.58

Base Dissociation Constant (pKb)

0.43

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.00

L865-0055 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

DGK Inhibitors Library (10558 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • Epigenetic
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with L865-0055 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L865-0055?
Check Price and Availability of L865-0055, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L865-0055 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L865-0055
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L865-0055
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L865-0055 available by request