L900-0225 Screening compound: 2-{3-[4-(2-chlorophenyl)piperazine-1-carbonyl]piperidin-1-yl}-3-phenoxypyrazine

L900-0225 Screening compound: 2-{3-[4-(2-chlorophenyl)piperazine-1-carbonyl]piperidin-1-yl}-3-phenoxypyrazine
L900-0225 Screening compound: 2-{3-[4-(2-chlorophenyl)piperazine-1-carbonyl]piperidin-1-yl}-3-phenoxypyrazine alternative view

Chemical Structure Depiction of ChemDiv screening compound L900-0225
2-{3-[4-(2-chlorophenyl)piperazine-1-carbonyl]piperidin-1-yl}-3-phenoxypyrazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L900-0225

Molecular Formula

C26H28ClN5O2 (C26 H28 ClN5 O2)

Compound Name

2-{3-[4-(2-chlorophenyl)piperazine-1-carbonyl]piperidin-1-yl}-3-phenoxypyrazine

IUPAC name

2-{3-[4-(2-chlorophenyl)piperazine-1-carbonyl]piperidin-1-yl}-3-phenoxypyrazine

SMILES

O=C(C(CCC1)CN1c1nccnc1Oc1ccccc1)N(CC1)CCN1c(cccc1)c1Cl

InChI

InChI=1S/C26H28ClN5O2/c27-22-10-4-5-11-23(22)30-15-17-31(18-16-30)26(33)20-7-6-14-32(19-20)24-25(29-13-12-28-24)34-21-8-2-1-3-9-21/h1-5,8-13,20H,6-7,14-19H2/t20-/m0/s1

InChI Key

GBEKJXACBDJNHO-FQEVSTJZSA-N

MDL Number (MFCD)

MFCD27485444

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

477.99

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.802

Distribution Coefficient, logD

4.802

Water Solubility, LogSw

-4.89

Polar Surface Area

48.766

Acid Dissociation Constant (pKa)

22.75

Base Dissociation Constant (pKb)

5.79

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

34.60

L900-0225 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

SmartTM Library (51161 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with L900-0225 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L900-0225?
Check Price and Availability of L900-0225, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L900-0225 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L900-0225
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L900-0225
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L900-0225 available by request