L933-0403 Screening compound: methyl 2-{[(1-{4-benzyl-3-oxo-3H,4H-pyrido[2,3-b]pyrazin-2-yl}piperidin-4-yl)carbamoyl]amino}-3-methylbutanoate

L933-0403 Screening compound: methyl 2-{[(1-{4-benzyl-3-oxo-3H,4H-pyrido[2,3-b]pyrazin-2-yl}piperidin-4-yl)carbamoyl]amino}-3-methylbutanoate
L933-0403 Screening compound: methyl 2-{[(1-{4-benzyl-3-oxo-3H,4H-pyrido[2,3-b]pyrazin-2-yl}piperidin-4-yl)carbamoyl]amino}-3-methylbutanoate alternative view

Chemical Structure Depiction of ChemDiv screening compound L933-0403
methyl 2-{[(1-{4-benzyl-3-oxo-3H,4H-pyrido[2,3-b]pyrazin-2-yl}piperidin-4-yl)carbamoyl]amino}-3-methylbutanoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L933-0403

Molecular Formula

C26H32N6O4 (C26 H32 N6 O4)

Compound Name

methyl 2-{[(1-{4-benzyl-3-oxo-3H,4H-pyrido[2,3-b]pyrazin-2-yl}piperidin-4-yl)carbamoyl]amino}-3-methylbutanoate

IUPAC name

methyl 2-{[(1-{4-benzyl-3-oxo-3H4H-pyrido[23-b]pyrazin-2-yl}piperidin-4-yl)carbamoyl]amino}-3-methylbutanoate

SMILES

CC(C)C(C(OC)=O)NC(NC(CC1)CCN1C1=Nc2cccnc2N(Cc2ccccc2)C1=O)=O

InChI

InChI=1S/C26H32N6O4/c1-17(2)21(25(34)36-3)30-26(35)28-19-11-14-31(15-12-19)23-24(33)32(16-18-8-5-4-6-9-18)22-20(29-23)10-7-13-27-22/h4-10,13,17,19,21H,11-12,14-16H2,1-3H3,(H2,28,30,35)/t21-/m0/s1

InChI Key

CLPYJJJGXQTNDX-NRFANRHFSA-N

MDL Number (MFCD)

MFCD27488231

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

492.58

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

2.809

Distribution Coefficient, logD

2.809

Water Solubility, LogSw

-3.23

Polar Surface Area

91.829

Acid Dissociation Constant (pKa)

16.32

Base Dissociation Constant (pKb)

3.04

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

42.30

L933-0403 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Chelators targeting matrix metalloproteinases library (8930 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Cardiovascular
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with L933-0403 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L933-0403?
Check Price and Availability of L933-0403, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L933-0403 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L933-0403
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L933-0403
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L933-0403 available by request