L933-0451 Screening compound: 1-(2,4-dimethoxyphenyl)-3-{1-[3-oxo-4-(prop-2-en-1-yl)-3H,4H-pyrido[2,3-b]pyrazin-2-yl]piperidin-4-yl}urea

L933-0451 Screening compound: 1-(2,4-dimethoxyphenyl)-3-{1-[3-oxo-4-(prop-2-en-1-yl)-3H,4H-pyrido[2,3-b]pyrazin-2-yl]piperidin-4-yl}urea
L933-0451 Screening compound: 1-(2,4-dimethoxyphenyl)-3-{1-[3-oxo-4-(prop-2-en-1-yl)-3H,4H-pyrido[2,3-b]pyrazin-2-yl]piperidin-4-yl}urea alternative view

Chemical Structure Depiction of ChemDiv screening compound L933-0451
1-(2,4-dimethoxyphenyl)-3-{1-[3-oxo-4-(prop-2-en-1-yl)-3H,4H-pyrido[2,3-b]pyrazin-2-yl]piperidin-4-yl}urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L933-0451

Molecular Formula

C24H28N6O4 (C24 H28 N6 O4)

Compound Name

1-(2,4-dimethoxyphenyl)-3-{1-[3-oxo-4-(prop-2-en-1-yl)-3H,4H-pyrido[2,3-b]pyrazin-2-yl]piperidin-4-yl}urea

IUPAC name

1-(24-dimethoxyphenyl)-3-{1-[3-oxo-4-(prop-2-en-1-yl)-3H4H-pyrido[23-b]pyrazin-2-yl]piperidin-4-yl}urea

SMILES

COc(cc1)cc(OC)c1NC(NC(CC1)CCN1C1=Nc2cccnc2N(CC=C)C1=O)=O

InChI

InChI=1S/C24H28N6O4/c1-4-12-30-21-19(6-5-11-25-21)27-22(23(30)31)29-13-9-16(10-14-29)26-24(32)28-18-8-7-17(33-2)15-20(18)34-3/h4-8,11,15-16H,1,9-10,12-14H2,2-3H3,(H2,26,28,32)

InChI Key

GHCNNKUKNLZKFO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27488254

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

464.52

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

2.120

Distribution Coefficient, logD

2.120

Water Solubility, LogSw

-2.91

Polar Surface Area

84.435

Acid Dissociation Constant (pKa)

12.49

Base Dissociation Constant (pKb)

4.12

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

L933-0451 in Drug Discovery

Included in Screening Libraries

Chelators targeting matrix metalloproteinases library (8930 compounds)

Anti-HIV1 Library (19540 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Cardiovascular
  • Antiviral
  • Infections
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with L933-0451 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L933-0451?
Check Price and Availability of L933-0451, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L933-0451 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L933-0451
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L933-0451
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L933-0451 available by request