L933-0487 Screening compound: methyl 3-[({1-[3-oxo-4-(prop-2-en-1-yl)-3H,4H-pyrido[2,3-b]pyrazin-2-yl]piperidin-4-yl}carbamoyl)amino]thiophene-2-carboxylate

L933-0487 Screening compound: methyl 3-[({1-[3-oxo-4-(prop-2-en-1-yl)-3H,4H-pyrido[2,3-b]pyrazin-2-yl]piperidin-4-yl}carbamoyl)amino]thiophene-2-carboxylate
L933-0487 Screening compound: methyl 3-[({1-[3-oxo-4-(prop-2-en-1-yl)-3H,4H-pyrido[2,3-b]pyrazin-2-yl]piperidin-4-yl}carbamoyl)amino]thiophene-2-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound L933-0487
methyl 3-[({1-[3-oxo-4-(prop-2-en-1-yl)-3H,4H-pyrido[2,3-b]pyrazin-2-yl]piperidin-4-yl}carbamoyl)amino]thiophene-2-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L933-0487

Molecular Formula

C22H24N6O4S (C22 H24 N6 O4 S)

Compound Name

methyl 3-[({1-[3-oxo-4-(prop-2-en-1-yl)-3H,4H-pyrido[2,3-b]pyrazin-2-yl]piperidin-4-yl}carbamoyl)amino]thiophene-2-carboxylate

IUPAC name

methyl 3-[({1-[3-oxo-4-(prop-2-en-1-yl)-3H4H-pyrido[23-b]pyrazin-2-yl]piperidin-4-yl}carbamoyl)amino]thiophene-2-carboxylate

SMILES

COC(c(scc1)c1NC(NC(CC1)CCN1C(C(N1CC=C)=O)=Nc2c1nccc2)=O)=O

InChI

InChI=1S/C22H24N6O4S/c1-3-10-28-18-16(5-4-9-23-18)25-19(20(28)29)27-11-6-14(7-12-27)24-22(31)26-15-8-13-33-17(15)21(30)32-2/h3-5,8-9,13-14H,1,6-7,10-12H2,2H3,(H2,24,26,31)

InChI Key

QWDFPGUGGOKIKV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27488273

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

468.54

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

1.794

Distribution Coefficient, logD

1.792

Water Solubility, LogSw

-2.31

Polar Surface Area

91.453

Acid Dissociation Constant (pKa)

10.03

Base Dissociation Constant (pKb)

4.12

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.80

L933-0487 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Chelators targeting matrix metalloproteinases library (8930 compounds)

Anti-HIV1 Library (19540 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Cardiovascular
  • Antiviral
  • Infections
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with L933-0487 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L933-0487?
Check Price and Availability of L933-0487, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L933-0487 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L933-0487
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L933-0487
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L933-0487 available by request