L934-0318 Screening compound: N-{5-[1-(4-chlorophenyl)-5-oxopyrrolidin-3-yl]-1,3,4-oxadiazol-2-yl}-4-(trifluoromethyl)benzamide

L934-0318 Screening compound: N-{5-[1-(4-chlorophenyl)-5-oxopyrrolidin-3-yl]-1,3,4-oxadiazol-2-yl}-4-(trifluoromethyl)benzamide
L934-0318 Screening compound: N-{5-[1-(4-chlorophenyl)-5-oxopyrrolidin-3-yl]-1,3,4-oxadiazol-2-yl}-4-(trifluoromethyl)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L934-0318
N-{5-[1-(4-chlorophenyl)-5-oxopyrrolidin-3-yl]-1,3,4-oxadiazol-2-yl}-4-(trifluoromethyl)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L934-0318

Molecular Formula

C20H14ClF3N4O3 (C20 H14 ClF3 N4 O3)

Compound Name

N-{5-[1-(4-chlorophenyl)-5-oxopyrrolidin-3-yl]-1,3,4-oxadiazol-2-yl}-4-(trifluoromethyl)benzamide

IUPAC name

N-{5-[1-(4-chlorophenyl)-5-oxopyrrolidin-3-yl]-134-oxadiazol-2-yl}-4-(trifluoromethyl)benzamide

SMILES

O=C(c1ccc(C(F)(F)F)cc1)Nc1nnc(C(CC2=O)CN2c(cc2)ccc2Cl)o1

InChI

InChI=1S/C20H14ClF3N4O3/c21-14-5-7-15(8-6-14)28-10-12(9-16(28)29)18-26-27-19(31-18)25-17(30)11-1-3-13(4-2-11)20(22,23)24/h1-8,12H,9-10H2,(H,25,27,30)/t12-/m1/s1

InChI Key

NIWWCWJYJBLSRN-GFCCVEGCSA-N

MDL Number (MFCD)

MFCD15137599

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

450.8

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.470

Distribution Coefficient, logD

1.717

Water Solubility, LogSw

-4.01

Polar Surface Area

71.908

Acid Dissociation Constant (pKa)

5.66

Base Dissociation Constant (pKb)

-2.57

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

20.00

L934-0318 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

C-Met Library (15277 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases
  • Kinases
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L934-0318 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L934-0318?
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What is the minimum amount of L934-0318 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L934-0318
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L934-0318
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L934-0318 available by request