L934-0578 Screening compound: 2,2-dimethyl-N-(5-{1-[4-(methylsulfanyl)phenyl]-5-oxopyrrolidin-3-yl}-1,3,4-oxadiazol-2-yl)propanamide

L934-0578 Screening compound: 2,2-dimethyl-N-(5-{1-[4-(methylsulfanyl)phenyl]-5-oxopyrrolidin-3-yl}-1,3,4-oxadiazol-2-yl)propanamide
L934-0578 Screening compound: 2,2-dimethyl-N-(5-{1-[4-(methylsulfanyl)phenyl]-5-oxopyrrolidin-3-yl}-1,3,4-oxadiazol-2-yl)propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L934-0578
2,2-dimethyl-N-(5-{1-[4-(methylsulfanyl)phenyl]-5-oxopyrrolidin-3-yl}-1,3,4-oxadiazol-2-yl)propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L934-0578

Molecular Formula

C18H22N4O3S (C18 H22 N4 O3 S)

Compound Name

2,2-dimethyl-N-(5-{1-[4-(methylsulfanyl)phenyl]-5-oxopyrrolidin-3-yl}-1,3,4-oxadiazol-2-yl)propanamide

IUPAC name

22-dimethyl-N-(5-{1-[4-(methylsulfanyl)phenyl]-5-oxopyrrolidin-3-yl}-134-oxadiazol-2-yl)propanamide

SMILES

CC(C)(C)C(Nc1nnc(C(CC2=O)CN2c(cc2)ccc2SC)o1)=O

InChI

InChI=1S/C18H22N4O3S/c1-18(2,3)16(24)19-17-21-20-15(25-17)11-9-14(23)22(10-11)12-5-7-13(26-4)8-6-12/h5-8,11H,9-10H2,1-4H3,(H,19,21,24)/t11-/m1/s1

InChI Key

JMRHZEFRAUNXNU-LLVKDONJSA-N

MDL Number (MFCD)

MFCD27488434

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

374.46

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.313

Distribution Coefficient, logD

1.583

Water Solubility, LogSw

-2.86

Polar Surface Area

72.179

Acid Dissociation Constant (pKa)

6.76

Base Dissociation Constant (pKb)

-1.98

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

44.40

L934-0578 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L934-0578 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L934-0578?
Check Price and Availability of L934-0578, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L934-0578 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L934-0578
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L934-0578
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L934-0578 available by request