L946-0109 Screening compound: 4-[5-(1-benzoylpiperidin-4-yl)-1,2,4-oxadiazol-3-yl]-N-(2-phenylethyl)benzamide

L946-0109 Screening compound: 4-[5-(1-benzoylpiperidin-4-yl)-1,2,4-oxadiazol-3-yl]-N-(2-phenylethyl)benzamide
L946-0109 Screening compound: 4-[5-(1-benzoylpiperidin-4-yl)-1,2,4-oxadiazol-3-yl]-N-(2-phenylethyl)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L946-0109
4-[5-(1-benzoylpiperidin-4-yl)-1,2,4-oxadiazol-3-yl]-N-(2-phenylethyl)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L946-0109

Molecular Formula

C29H28N4O3 (C29 H28 N4 O3)

Compound Name

4-[5-(1-benzoylpiperidin-4-yl)-1,2,4-oxadiazol-3-yl]-N-(2-phenylethyl)benzamide

IUPAC name

4-[5-(1-benzoylpiperidin-4-yl)-124-oxadiazol-3-yl]-N-(2-phenylethyl)benzamide

SMILES

O=C(c(cc1)ccc1-c1noc(C(CC2)CCN2C(c2ccccc2)=O)n1)NCCc1ccccc1

InChI

InChI=1S/C29H28N4O3/c34-27(30-18-15-21-7-3-1-4-8-21)23-13-11-22(12-14-23)26-31-28(36-32-26)24-16-19-33(20-17-24)29(35)25-9-5-2-6-10-25/h1-14,24H,15-20H2,(H,30,34)

InChI Key

HVHCGXYVRDZSDX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27488921

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

480.57

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.448

Distribution Coefficient, logD

4.448

Water Solubility, LogSw

-4.39

Polar Surface Area

72.547

Acid Dissociation Constant (pKa)

13.15

Base Dissociation Constant (pKb)

-2.40

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

24.10

L946-0109 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L946-0109 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L946-0109?
Check Price and Availability of L946-0109, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L946-0109 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L946-0109
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L946-0109
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L946-0109 available by request