L957-0463 Screening compound: 8-{5-[4-(piperidine-1-sulfonyl)phenyl]-1,3,4-oxadiazole-2-carbonyl}-1,4-dioxa-8-azaspiro[4.5]decane

L957-0463 Screening compound: 8-{5-[4-(piperidine-1-sulfonyl)phenyl]-1,3,4-oxadiazole-2-carbonyl}-1,4-dioxa-8-azaspiro[4.5]decane
L957-0463 Screening compound: 8-{5-[4-(piperidine-1-sulfonyl)phenyl]-1,3,4-oxadiazole-2-carbonyl}-1,4-dioxa-8-azaspiro[4.5]decane alternative view

Chemical Structure Depiction of ChemDiv screening compound L957-0463
8-{5-[4-(piperidine-1-sulfonyl)phenyl]-1,3,4-oxadiazole-2-carbonyl}-1,4-dioxa-8-azaspiro[4.5]decane

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L957-0463

Molecular Formula

C21H26N4O6S (C21 H26 N4 O6 S)

Compound Name

8-{5-[4-(piperidine-1-sulfonyl)phenyl]-1,3,4-oxadiazole-2-carbonyl}-1,4-dioxa-8-azaspiro[4.5]decane

IUPAC name

8-{5-[4-(piperidine-1-sulfonyl)phenyl]-134-oxadiazole-2-carbonyl}-14-dioxa-8-azaspiro[4.5]decane

SMILES

O=C(c1nnc(-c(cc2)ccc2S(N2CCCCC2)(=O)=O)o1)N(CC1)CCC11OCCO1

InChI

InChI=1S/C21H26N4O6S/c26-20(24-12-8-21(9-13-24)29-14-15-30-21)19-23-22-18(31-19)16-4-6-17(7-5-16)32(27,28)25-10-2-1-3-11-25/h4-7H,1-3,8-15H2

InChI Key

RPKWRXZKOTVIHG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15137709

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

462.53

Hydrogen Bond Acceptors Count

12.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

1.215

Distribution Coefficient, logD

1.215

Water Solubility, LogSw

-2.35

Polar Surface Area

93.550

Acid Dissociation Constant (pKa)

27.45

Base Dissociation Constant (pKb)

-2.87

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

57.10

L957-0463 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L957-0463 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L957-0463?
Check Price and Availability of L957-0463, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L957-0463 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L957-0463
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L957-0463
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L957-0463 available by request