L958-1223 Screening compound: 2-{2-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-1H-pyrrol-1-yl}-N-[2-(thiophen-2-yl)ethyl]acetamide

L958-1223 Screening compound: 2-{2-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-1H-pyrrol-1-yl}-N-[2-(thiophen-2-yl)ethyl]acetamide
L958-1223 Screening compound: 2-{2-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-1H-pyrrol-1-yl}-N-[2-(thiophen-2-yl)ethyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L958-1223
2-{2-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-1H-pyrrol-1-yl}-N-[2-(thiophen-2-yl)ethyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L958-1223

Molecular Formula

C21H18ClN3OS2 (C21 H18 ClN3 OS2)

Compound Name

2-{2-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-1H-pyrrol-1-yl}-N-[2-(thiophen-2-yl)ethyl]acetamide

IUPAC name

2-{2-[4-(4-chlorophenyl)-13-thiazol-2-yl]-1H-pyrrol-1-yl}-N-[2-(thiophen-2-yl)ethyl]acetamide

SMILES

O=C(Cn1c(-c2nc(-c(cc3)ccc3Cl)cs2)ccc1)NCCc1cccs1

InChI

InChI=1S/C21H18ClN3OS2/c22-16-7-5-15(6-8-16)18-14-28-21(24-18)19-4-1-11-25(19)13-20(26)23-10-9-17-3-2-12-27-17/h1-8,11-12,14H,9-10,13H2,(H,23,26)

InChI Key

WWQGTSWIQNHKPK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15137745

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

427.98

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.557

Distribution Coefficient, logD

5.557

Water Solubility, LogSw

-6.11

Polar Surface Area

36.622

Acid Dissociation Constant (pKa)

14.42

Base Dissociation Constant (pKb)

2.45

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

14.30

L958-1223 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with L958-1223 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L958-1223?
Check Price and Availability of L958-1223, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L958-1223 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L958-1223
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L958-1223
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L958-1223 available by request