L960-0495 Screening compound: 3-{[3-(4-methylphenyl)-6-oxo-1,6-dihydropyridazin-1-yl]methyl}-N-[2-(4-sulfamoylphenyl)ethyl]-1,2,4-oxadiazole-5-carboxamide

L960-0495 Screening compound: 3-{[3-(4-methylphenyl)-6-oxo-1,6-dihydropyridazin-1-yl]methyl}-N-[2-(4-sulfamoylphenyl)ethyl]-1,2,4-oxadiazole-5-carboxamide
L960-0495 Screening compound: 3-{[3-(4-methylphenyl)-6-oxo-1,6-dihydropyridazin-1-yl]methyl}-N-[2-(4-sulfamoylphenyl)ethyl]-1,2,4-oxadiazole-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L960-0495
3-{[3-(4-methylphenyl)-6-oxo-1,6-dihydropyridazin-1-yl]methyl}-N-[2-(4-sulfamoylphenyl)ethyl]-1,2,4-oxadiazole-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L960-0495

Molecular Formula

C23H22N6O5S (C23 H22 N6 O5 S)

Compound Name

3-{[3-(4-methylphenyl)-6-oxo-1,6-dihydropyridazin-1-yl]methyl}-N-[2-(4-sulfamoylphenyl)ethyl]-1,2,4-oxadiazole-5-carboxamide

IUPAC name

3-{[3-(4-methylphenyl)-6-oxo-16-dihydropyridazin-1-yl]methyl}-N-[2-(4-sulfamoylphenyl)ethyl]-124-oxadiazole-5-carboxamide

SMILES

Cc(cc1)ccc1C(C=C1)=NN(Cc2noc(C(NCCc(cc3)ccc3S(N)(=O)=O)=O)n2)C1=O

InChI

InChI=1S/C23H22N6O5S/c1-15-2-6-17(7-3-15)19-10-11-21(30)29(27-19)14-20-26-23(34-28-20)22(31)25-13-12-16-4-8-18(9-5-16)35(24,32)33/h2-11H,12-14H2,1H3,(H,25,31)(H2,24,32,33)

InChI Key

MEJKKSOCWREBEM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15137788

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

494.53

Hydrogen Bond Acceptors Count

13.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

11

Partition Coefficient, logP

1.237

Distribution Coefficient, logD

1.236

Water Solubility, LogSw

-2.33

Polar Surface Area

136.345

Acid Dissociation Constant (pKa)

10.18

Base Dissociation Constant (pKb)

1.03

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.40

L960-0495 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

SH2 PTB Focused Library (6188 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with L960-0495 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L960-0495?
Check Price and Availability of L960-0495, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L960-0495 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L960-0495
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L960-0495
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L960-0495 available by request