M008-1662 Screening compound: 5-fluoro-N-{4-methyl-5-[4-(pyridin-2-yl)piperazine-1-carbonyl]-1,3-thiazol-2-yl}pyridin-2-amine

M008-1662 Screening compound: 5-fluoro-N-{4-methyl-5-[4-(pyridin-2-yl)piperazine-1-carbonyl]-1,3-thiazol-2-yl}pyridin-2-amine
M008-1662 Screening compound: 5-fluoro-N-{4-methyl-5-[4-(pyridin-2-yl)piperazine-1-carbonyl]-1,3-thiazol-2-yl}pyridin-2-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound M008-1662
5-fluoro-N-{4-methyl-5-[4-(pyridin-2-yl)piperazine-1-carbonyl]-1,3-thiazol-2-yl}pyridin-2-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M008-1662

Molecular Formula

C19H19FN6OS (C19 H19 FN6 OS)

Compound Name

5-fluoro-N-{4-methyl-5-[4-(pyridin-2-yl)piperazine-1-carbonyl]-1,3-thiazol-2-yl}pyridin-2-amine

IUPAC name

5-fluoro-N-{4-methyl-5-[4-(pyridin-2-yl)piperazine-1-carbonyl]-13-thiazol-2-yl}pyridin-2-amine

SMILES

Cc1c(C(N(CC2)CCN2c2ncccc2)=O)sc(Nc(cc2)ncc2F)n1

InChI

InChI=1S/C19H19FN6OS/c1-13-17(28-19(23-13)24-15-6-5-14(20)12-22-15)18(27)26-10-8-25(9-11-26)16-4-2-3-7-21-16/h2-7,12H,8-11H2,1H3,(H,22,23,24)

InChI Key

IOHNCAGVBJRJGB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27491828

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

398.46

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.984

Distribution Coefficient, logD

3.975

Water Solubility, LogSw

-3.84

Polar Surface Area

57.899

Acid Dissociation Constant (pKa)

13.93

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.30

M008-1662 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Nervous system
  • Cardiovascular
Targets:
  • GPCR
  • Kinases
  • Proteases
  • Ion Channels
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with M008-1662 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M008-1662?
Check Price and Availability of M008-1662, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M008-1662 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M008-1662
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M008-1662
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M008-1662 available by request