M127-0605 Screening compound: N-(4-ethylphenyl)-1-(4-fluorophenyl)-1H-indazole-3-carboxamide

M127-0605 Screening compound: N-(4-ethylphenyl)-1-(4-fluorophenyl)-1H-indazole-3-carboxamide
M127-0605 Screening compound: N-(4-ethylphenyl)-1-(4-fluorophenyl)-1H-indazole-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M127-0605
N-(4-ethylphenyl)-1-(4-fluorophenyl)-1H-indazole-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M127-0605

Molecular Formula

C22H18FN3O (C22 H18 FN3 O)

Compound Name

N-(4-ethylphenyl)-1-(4-fluorophenyl)-1H-indazole-3-carboxamide

IUPAC name

N-(4-ethylphenyl)-1-(4-fluorophenyl)-1H-indazole-3-carboxamide

SMILES

CCc(cc1)ccc1NC(c(c1c2cccc1)nn2-c(cc1)ccc1F)=O

InChI

InChI=1S/C22H18FN3O/c1-2-15-7-11-17(12-8-15)24-22(27)21-19-5-3-4-6-20(19)26(25-21)18-13-9-16(23)10-14-18/h3-14H,2H2,1H3,(H,24,27)

InChI Key

KGHJFIFEPBQMIL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27498483

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

359.4

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.413

Distribution Coefficient, logD

5.413

Water Solubility, LogSw

-5.66

Polar Surface Area

37.444

Acid Dissociation Constant (pKa)

13.88

Base Dissociation Constant (pKb)

-1.69

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.10

M127-0605 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Glucocorticoid receptors Library (4806 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
Mechanism of action:
  • Epigenetic
  • Receptor's ligands
Targets:
  • Nuclear receptors

References: we are preparing a list of scientific research reports with M127-0605 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M127-0605?
Check Price and Availability of M127-0605, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M127-0605 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M127-0605
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M127-0605
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M127-0605 available by request