M143-0627 Screening compound: 2-{[7-(4-methoxyphenyl)pyrimido[4,5-d][1,3]diazin-4-yl]sulfanyl}-N-(3,4,5-trimethoxyphenyl)acetamide

M143-0627 Screening compound: 2-{[7-(4-methoxyphenyl)pyrimido[4,5-d][1,3]diazin-4-yl]sulfanyl}-N-(3,4,5-trimethoxyphenyl)acetamide
M143-0627 Screening compound: 2-{[7-(4-methoxyphenyl)pyrimido[4,5-d][1,3]diazin-4-yl]sulfanyl}-N-(3,4,5-trimethoxyphenyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M143-0627
2-{[7-(4-methoxyphenyl)pyrimido[4,5-d][1,3]diazin-4-yl]sulfanyl}-N-(3,4,5-trimethoxyphenyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M143-0627

Molecular Formula

C24H23N5O5S (C24 H23 N5 O5 S)

Compound Name

2-{[7-(4-methoxyphenyl)pyrimido[4,5-d][1,3]diazin-4-yl]sulfanyl}-N-(3,4,5-trimethoxyphenyl)acetamide

IUPAC name

2-{[7-(4-methoxyphenyl)pyrimido[45-d][13]diazin-4-yl]sulfanyl}-N-(345-trimethoxyphenyl)acetamide

SMILES

COc(cc1)ccc1-c1ncc2c(SCC(Nc(cc3OC)cc(OC)c3OC)=O)ncnc2n1

InChI

InChI=1S/C24H23N5O5S/c1-31-16-7-5-14(6-8-16)22-25-11-17-23(29-22)26-13-27-24(17)35-12-20(30)28-15-9-18(32-2)21(34-4)19(10-15)33-3/h5-11,13H,12H2,1-4H3,(H,28,30)

InChI Key

LAFHOFWMQXGRQU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27532298

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

493.54

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

3.401

Distribution Coefficient, logD

3.400

Water Solubility, LogSw

-3.72

Polar Surface Area

93.442

Acid Dissociation Constant (pKa)

10.49

Base Dissociation Constant (pKb)

2.55

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.80

M143-0627 in Drug Discovery

Included in Screening Libraries

ACE2 Library (3043 compounds)

CORONAVIRUS Library (20774 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system

References: we are preparing a list of scientific research reports with M143-0627 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M143-0627?
Check Price and Availability of M143-0627, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M143-0627 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M143-0627
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M143-0627
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M143-0627 available by request