M144-0886 Screening compound: N-(5-tert-butyl-2-hydroxyphenyl)-1-[4-(diethylsulfamoyl)phenyl]-1H-imidazole-4-carboxamide

M144-0886 Screening compound: N-(5-tert-butyl-2-hydroxyphenyl)-1-[4-(diethylsulfamoyl)phenyl]-1H-imidazole-4-carboxamide
M144-0886 Screening compound: N-(5-tert-butyl-2-hydroxyphenyl)-1-[4-(diethylsulfamoyl)phenyl]-1H-imidazole-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M144-0886
N-(5-tert-butyl-2-hydroxyphenyl)-1-[4-(diethylsulfamoyl)phenyl]-1H-imidazole-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M144-0886

Molecular Formula

C24H30N4O4S (C24 H30 N4 O4 S)

Compound Name

N-(5-tert-butyl-2-hydroxyphenyl)-1-[4-(diethylsulfamoyl)phenyl]-1H-imidazole-4-carboxamide

IUPAC name

N-(5-tert-butyl-2-hydroxyphenyl)-1-[4-(diethylsulfamoyl)phenyl]-1H-imidazole-4-carboxamide

SMILES

CCN(CC)S(c(cc1)ccc1-n1cnc(C(Nc(cc(C(C)(C)C)cc2)c2O)=O)c1)(=O)=O

InChI

InChI=1S/C24H30N4O4S/c1-6-28(7-2)33(31,32)19-11-9-18(10-12-19)27-15-21(25-16-27)23(30)26-20-14-17(24(3,4)5)8-13-22(20)29/h8-16,29H,6-7H2,1-5H3,(H,26,30)

InChI Key

OSAXYETXRZISMK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27532379

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

470.59

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.681

Distribution Coefficient, logD

4.679

Water Solubility, LogSw

-4.05

Polar Surface Area

82.514

Acid Dissociation Constant (pKa)

9.74

Base Dissociation Constant (pKb)

1.99

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

M144-0886 in Drug Discovery

Included in Screening Libraries

Hsp90-Targeted Library (11355 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system

References: we are preparing a list of scientific research reports with M144-0886 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M144-0886?
Check Price and Availability of M144-0886, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M144-0886 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M144-0886
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M144-0886
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M144-0886 available by request