M180-0166 Screening compound: N-(2-cyanophenyl)-2-{[2-(4-fluorophenyl)-6-methylpyrimidin-4-yl]oxy}acetamide

M180-0166 Screening compound: N-(2-cyanophenyl)-2-{[2-(4-fluorophenyl)-6-methylpyrimidin-4-yl]oxy}acetamide
M180-0166 Screening compound: N-(2-cyanophenyl)-2-{[2-(4-fluorophenyl)-6-methylpyrimidin-4-yl]oxy}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M180-0166
N-(2-cyanophenyl)-2-{[2-(4-fluorophenyl)-6-methylpyrimidin-4-yl]oxy}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M180-0166

Molecular Formula

C20H15FN4O2 (C20 H15 FN4 O2)

Compound Name

N-(2-cyanophenyl)-2-{[2-(4-fluorophenyl)-6-methylpyrimidin-4-yl]oxy}acetamide

IUPAC name

N-(2-cyanophenyl)-2-{[2-(4-fluorophenyl)-6-methylpyrimidin-4-yl]oxy}acetamide

SMILES

Cc1nc(-c(cc2)ccc2F)nc(OCC(Nc(cccc2)c2C#N)=O)c1

InChI

InChI=1S/C20H15FN4O2/c1-13-10-19(25-20(23-13)14-6-8-16(21)9-7-14)27-12-18(26)24-17-5-3-2-4-15(17)11-22/h2-10H,12H2,1H3,(H,24,26)

InChI Key

FWDKIGCWSGUQLL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27533559

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

362.36

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.000

Distribution Coefficient, logD

3.999

Water Solubility, LogSw

-4.17

Polar Surface Area

64.980

Acid Dissociation Constant (pKa)

10.01

Base Dissociation Constant (pKb)

2.39

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.00

M180-0166 in Drug Discovery

Included in Screening Libraries

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with M180-0166 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M180-0166?
Check Price and Availability of M180-0166, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M180-0166 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M180-0166
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M180-0166
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M180-0166 available by request