M182-0074 Screening compound: 2-[4-(2-methoxyphenyl)piperazin-1-yl]-6-(piperidine-1-sulfonyl)quinoxaline

M182-0074 Screening compound: 2-[4-(2-methoxyphenyl)piperazin-1-yl]-6-(piperidine-1-sulfonyl)quinoxaline
M182-0074 Screening compound: 2-[4-(2-methoxyphenyl)piperazin-1-yl]-6-(piperidine-1-sulfonyl)quinoxaline alternative view

Chemical Structure Depiction of ChemDiv screening compound M182-0074
2-[4-(2-methoxyphenyl)piperazin-1-yl]-6-(piperidine-1-sulfonyl)quinoxaline

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M182-0074

Molecular Formula

C24H29N5O3S (C24 H29 N5 O3 S)

Compound Name

2-[4-(2-methoxyphenyl)piperazin-1-yl]-6-(piperidine-1-sulfonyl)quinoxaline

IUPAC name

2-[4-(2-methoxyphenyl)piperazin-1-yl]-6-(piperidine-1-sulfonyl)quinoxaline

SMILES

COc(cccc1)c1N(CC1)CCN1c1cnc(cc(cc2)S(N3CCCCC3)(=O)=O)c2n1

InChI

InChI=1S/C24H29N5O3S/c1-32-23-8-4-3-7-22(23)27-13-15-28(16-14-27)24-18-25-21-17-19(9-10-20(21)26-24)33(30,31)29-11-5-2-6-12-29/h3-4,7-10,17-18H,2,5-6,11-16H2,1H3

InChI Key

QRQKBGFOTIABAB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27533742

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

467.59

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.188

Distribution Coefficient, logD

4.188

Water Solubility, LogSw

-4.25

Polar Surface Area

62.910

Acid Dissociation Constant (pKa)

23.99

Base Dissociation Constant (pKb)

6.45

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

41.70

M182-0074 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with M182-0074 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M182-0074?
Check Price and Availability of M182-0074, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M182-0074 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M182-0074
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M182-0074
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M182-0074 available by request