M258-1254 Screening compound: N~3~-methyl-1-{3-[(phenylsulfonyl)amino]-2-pyridyl}-3-piperidinecarboxamide

M258-1254 Screening compound: N~3~-methyl-1-{3-[(phenylsulfonyl)amino]-2-pyridyl}-3-piperidinecarboxamide
M258-1254 Screening compound: N~3~-methyl-1-{3-[(phenylsulfonyl)amino]-2-pyridyl}-3-piperidinecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M258-1254
N~3~-methyl-1-{3-[(phenylsulfonyl)amino]-2-pyridyl}-3-piperidinecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M258-1254

Molecular Formula

C18H22N4O3S (C18 H22 N4 O3 S)

Compound Name

N~3~-methyl-1-{3-[(phenylsulfonyl)amino]-2-pyridyl}-3-piperidinecarboxamide

IUPAC name

n/a

SMILES

CNC(C(CCC1)CN1c(nccc1)c1NS(c1ccccc1)(=O)=O)=O

InChI

InChI=1S/C18H22N4O3S/c1-19-18(23)14-7-6-12-22(13-14)17-16(10-5-11-20-17)21-26(24,25)15-8-3-2-4-9-15/h2-5,8-11,14,21H,6-7,12-13H2,1H3,(H,19,23)/t14-/m0/s1

InChI Key

ZMYABMRXSMBQBR-AWEZNQCLSA-N

MDL Number (MFCD)

MFCD27534616

Chemical and Physical Properties

Saltdata

CF3COOH

Molecular Weight

374.46

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.432

Distribution Coefficient, logD

-0.697

Water Solubility, LogSw

-2.60

Polar Surface Area

77.392

Acid Dissociation Constant (pKa)

5.69

Base Dissociation Constant (pKb)

5.55

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

33.30

M258-1254 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases
  • Kinases
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with M258-1254 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M258-1254?
Check Price and Availability of M258-1254, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M258-1254 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M258-1254
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M258-1254
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M258-1254 available by request