M274-0237 Screening compound: 1-{3-[2-(3-methylphenyl)pyrimidin-4-yl]piperidin-1-yl}ethan-1-one

M274-0237 Screening compound: 1-{3-[2-(3-methylphenyl)pyrimidin-4-yl]piperidin-1-yl}ethan-1-one
M274-0237 Screening compound: 1-{3-[2-(3-methylphenyl)pyrimidin-4-yl]piperidin-1-yl}ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound M274-0237
1-{3-[2-(3-methylphenyl)pyrimidin-4-yl]piperidin-1-yl}ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M274-0237

Molecular Formula

C18H21N3O (C18 H21 N3 O)

Compound Name

1-{3-[2-(3-methylphenyl)pyrimidin-4-yl]piperidin-1-yl}ethan-1-one

IUPAC name

1-{3-[2-(3-methylphenyl)pyrimidin-4-yl]piperidin-1-yl}ethan-1-one

SMILES

CC(N(CCC1)CC1c1nc(-c2cc(C)ccc2)ncc1)=O

InChI

InChI=1S/C18H21N3O/c1-13-5-3-6-15(11-13)18-19-9-8-17(20-18)16-7-4-10-21(12-16)14(2)22/h3,5-6,8-9,11,16H,4,7,10,12H2,1-2H3/t16-/m0/s1

InChI Key

NTYJIDLVISJNFZ-INIZCTEOSA-N

MDL Number (MFCD)

MFCD27534873

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

295.38

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

2.852

Distribution Coefficient, logD

2.851

Water Solubility, LogSw

-2.93

Polar Surface Area

36.020

Acid Dissociation Constant (pKa)

24.36

Base Dissociation Constant (pKb)

4.50

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

38.90

M274-0237 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

Fragments Library (11262 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
  • Cardiovascular
Structure:
  • Fragments
  • Cyclic compounds
Mechanism of action:
  • PPI modulators
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with M274-0237 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M274-0237?
Check Price and Availability of M274-0237, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M274-0237 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M274-0237
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M274-0237
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M274-0237 available by request