M283-1727 Screening compound: N-(4-chloro-2-methylphenyl)-4-{[2-(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]methyl}benzamide

M283-1727 Screening compound: N-(4-chloro-2-methylphenyl)-4-{[2-(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]methyl}benzamide
M283-1727 Screening compound: N-(4-chloro-2-methylphenyl)-4-{[2-(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]methyl}benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M283-1727
N-(4-chloro-2-methylphenyl)-4-{[2-(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]methyl}benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M283-1727

Molecular Formula

C22H16ClF3N4O (C22 H16 ClF3 N4 O)

Compound Name

N-(4-chloro-2-methylphenyl)-4-{[2-(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]methyl}benzamide

IUPAC name

N-(4-chloro-2-methylphenyl)-4-{[2-(trifluoromethyl)-3H-imidazo[45-b]pyridin-3-yl]methyl}benzamide

SMILES

Cc(cc(cc1)Cl)c1NC(c1ccc(Cn2c3ncccc3nc2C(F)(F)F)cc1)=O

InChI

InChI=1S/C22H16ClF3N4O/c1-13-11-16(23)8-9-17(13)28-20(31)15-6-4-14(5-7-15)12-30-19-18(3-2-10-27-19)29-21(30)22(24,25)26/h2-11H,12H2,1H3,(H,28,31)

InChI Key

IWORRDOUARVTMF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15141547

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

444.84

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.330

Distribution Coefficient, logD

5.321

Water Solubility, LogSw

-5.96

Polar Surface Area

42.467

Acid Dissociation Constant (pKa)

9.07

Base Dissociation Constant (pKb)

1.84

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.60

M283-1727 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with M283-1727 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M283-1727?
Check Price and Availability of M283-1727, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M283-1727 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M283-1727
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M283-1727
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M283-1727 available by request