M286-1318 Screening compound: N~4~-[(1-methyl-1H-1,3-benzimidazol-2-yl)methyl]-3-(1-pyrrolidinylmethyl)-1H-indole-4-carboxamide

M286-1318 Screening compound: N~4~-[(1-methyl-1H-1,3-benzimidazol-2-yl)methyl]-3-(1-pyrrolidinylmethyl)-1H-indole-4-carboxamide
M286-1318 Screening compound: N~4~-[(1-methyl-1H-1,3-benzimidazol-2-yl)methyl]-3-(1-pyrrolidinylmethyl)-1H-indole-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M286-1318
N~4~-[(1-methyl-1H-1,3-benzimidazol-2-yl)methyl]-3-(1-pyrrolidinylmethyl)-1H-indole-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M286-1318

Molecular Formula

C23H25N5O (C23 H25 N5 O)

Compound Name

N~4~-[(1-methyl-1H-1,3-benzimidazol-2-yl)methyl]-3-(1-pyrrolidinylmethyl)-1H-indole-4-carboxamide

IUPAC name

n/a

SMILES

Cn1c(cccc2)c2nc1CNC(c1c(c(CN2CCCC2)c[nH]2)c2ccc1)=O

InChI

InChI=1S/C23H25N5O/c1-27-20-10-3-2-8-18(20)26-21(27)14-25-23(29)17-7-6-9-19-22(17)16(13-24-19)15-28-11-4-5-12-28/h2-3,6-10,13,24H,4-5,11-12,14-15H2,1H3,(H,25,29)

InChI Key

YAYDZACGIWYWAQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27535141

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

387.48

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.343

Distribution Coefficient, logD

0.458

Water Solubility, LogSw

-3.91

Polar Surface Area

50.608

Acid Dissociation Constant (pKa)

12.14

Base Dissociation Constant (pKb)

10.28

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.40

M286-1318 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Immunological Library (6760 compounds)

Indole Derivatives (10091 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Indoleamine 2,3-dioxygenase 1 Focused Library (5816 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Immune system
  • Cancer
  • Digestive system
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Immune system
Structure:
  • Cyclic compounds
  • Mimetics
Mechanism of action:
  • PPI modulators
  • PPI modulators
Targets:
  • Others

References: we are preparing a list of scientific research reports with M286-1318 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M286-1318?
Check Price and Availability of M286-1318, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M286-1318 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M286-1318
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M286-1318
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M286-1318 available by request