M347-0172 Screening compound: 2-[2-(4-methyl-1,3-thiazol-2-yl)-4-(morpholine-4-sulfonyl)-1H-pyrrol-1-yl]-1-(pyrrolidin-1-yl)ethan-1-one

M347-0172 Screening compound: 2-[2-(4-methyl-1,3-thiazol-2-yl)-4-(morpholine-4-sulfonyl)-1H-pyrrol-1-yl]-1-(pyrrolidin-1-yl)ethan-1-one
M347-0172 Screening compound: 2-[2-(4-methyl-1,3-thiazol-2-yl)-4-(morpholine-4-sulfonyl)-1H-pyrrol-1-yl]-1-(pyrrolidin-1-yl)ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound M347-0172
2-[2-(4-methyl-1,3-thiazol-2-yl)-4-(morpholine-4-sulfonyl)-1H-pyrrol-1-yl]-1-(pyrrolidin-1-yl)ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M347-0172

Molecular Formula

C18H24N4O4S2 (C18 H24 N4 O4 S2)

Compound Name

2-[2-(4-methyl-1,3-thiazol-2-yl)-4-(morpholine-4-sulfonyl)-1H-pyrrol-1-yl]-1-(pyrrolidin-1-yl)ethan-1-one

IUPAC name

2-[2-(4-methyl-13-thiazol-2-yl)-4-(morpholine-4-sulfonyl)-1H-pyrrol-1-yl]-1-(pyrrolidin-1-yl)ethan-1-one

SMILES

Cc1csc(-c2cc(S(N3CCOCC3)(=O)=O)cn2CC(N2CCCC2)=O)n1

InChI

InChI=1S/C18H24N4O4S2/c1-14-13-27-18(19-14)16-10-15(28(24,25)22-6-8-26-9-7-22)11-21(16)12-17(23)20-4-2-3-5-20/h10-11,13H,2-9,12H2,1H3

InChI Key

QZSRRJQNLFBHFW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27537811

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

424.55

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.224

Distribution Coefficient, logD

1.224

Water Solubility, LogSw

-1.96

Polar Surface Area

67.639

Acid Dissociation Constant (pKa)

23.68

Base Dissociation Constant (pKb)

1.10

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

55.60

M347-0172 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS MPO Library (28609 compounds)

GPCR Targeted Library (31838 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with M347-0172 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M347-0172?
Check Price and Availability of M347-0172, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M347-0172 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M347-0172
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M347-0172
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M347-0172 available by request