M348-0319 Screening compound: 8-({3,5-dimethyl-1-[6-(4-methylphenyl)pyridazin-3-yl]-1H-pyrazol-4-yl}sulfonyl)-1,4-dioxa-8-azaspiro[4.5]decane

M348-0319 Screening compound: 8-({3,5-dimethyl-1-[6-(4-methylphenyl)pyridazin-3-yl]-1H-pyrazol-4-yl}sulfonyl)-1,4-dioxa-8-azaspiro[4.5]decane
M348-0319 Screening compound: 8-({3,5-dimethyl-1-[6-(4-methylphenyl)pyridazin-3-yl]-1H-pyrazol-4-yl}sulfonyl)-1,4-dioxa-8-azaspiro[4.5]decane alternative view

Chemical Structure Depiction of ChemDiv screening compound M348-0319
8-({3,5-dimethyl-1-[6-(4-methylphenyl)pyridazin-3-yl]-1H-pyrazol-4-yl}sulfonyl)-1,4-dioxa-8-azaspiro[4.5]decane

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M348-0319

Molecular Formula

C23H27N5O4S (C23 H27 N5 O4 S)

Compound Name

8-({3,5-dimethyl-1-[6-(4-methylphenyl)pyridazin-3-yl]-1H-pyrazol-4-yl}sulfonyl)-1,4-dioxa-8-azaspiro[4.5]decane

IUPAC name

8-({35-dimethyl-1-[6-(4-methylphenyl)pyridazin-3-yl]-1H-pyrazol-4-yl}sulfonyl)-14-dioxa-8-azaspiro[4.5]decane

SMILES

Cc(n(-c(cc1)nnc1-c1ccc(C)cc1)nc1C)c1S(N(CC1)CCC11OCCO1)(=O)=O

InChI

InChI=1S/C23H27N5O4S/c1-16-4-6-19(7-5-16)20-8-9-21(25-24-20)28-18(3)22(17(2)26-28)33(29,30)27-12-10-23(11-13-27)31-14-15-32-23/h4-9H,10-15H2,1-3H3

InChI Key

JLMAGKGIECXGGW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27538075

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

469.56

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.539

Distribution Coefficient, logD

2.483

Water Solubility, LogSw

-2.58

Polar Surface Area

81.739

Acid Dissociation Constant (pKa)

25.77

Base Dissociation Constant (pKb)

6.54

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

43.50

M348-0319 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Antiviral
  • Infections
  • Immune system

References: we are preparing a list of scientific research reports with M348-0319 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M348-0319?
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What is the minimum amount of M348-0319 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M348-0319
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M348-0319
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M348-0319 available by request