M373-1548 Screening compound: N-(2-fluorophenyl)-4-[1-(thiophene-2-carbonyl)piperidin-3-yl]pyrimidin-2-amine

M373-1548 Screening compound: N-(2-fluorophenyl)-4-[1-(thiophene-2-carbonyl)piperidin-3-yl]pyrimidin-2-amine
M373-1548 Screening compound: N-(2-fluorophenyl)-4-[1-(thiophene-2-carbonyl)piperidin-3-yl]pyrimidin-2-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound M373-1548
N-(2-fluorophenyl)-4-[1-(thiophene-2-carbonyl)piperidin-3-yl]pyrimidin-2-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M373-1548

Molecular Formula

C20H19FN4OS (C20 H19 FN4 OS)

Compound Name

N-(2-fluorophenyl)-4-[1-(thiophene-2-carbonyl)piperidin-3-yl]pyrimidin-2-amine

IUPAC name

N-(2-fluorophenyl)-4-[1-(thiophene-2-carbonyl)piperidin-3-yl]pyrimidin-2-amine

SMILES

O=C(c1cccs1)N(CCC1)CC1c1nc(Nc(cccc2)c2F)ncc1

InChI

InChI=1S/C20H19FN4OS/c21-15-6-1-2-7-17(15)24-20-22-10-9-16(23-20)14-5-3-11-25(13-14)19(26)18-8-4-12-27-18/h1-2,4,6-10,12,14H,3,5,11,13H2,(H,22,23,24)/t14-/m0/s1

InChI Key

XEYUBWKFUJUODV-AWEZNQCLSA-N

MDL Number (MFCD)

MFCD27539313

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

382.46

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.060

Distribution Coefficient, logD

4.060

Water Solubility, LogSw

-4.06

Polar Surface Area

45.919

Acid Dissociation Constant (pKa)

17.02

Base Dissociation Constant (pKb)

4.46

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

25.00

M373-1548 in Drug Discovery

Included in Screening Libraries

Immunological Library (6760 compounds)

Protein-Protein Interaction Library (218420 compounds)

Antibacterial Compounds Library (13827 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Indoleamine 2,3-dioxygenase 1 Focused Library (5816 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Infections
  • Immune system
  • animal
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
  • Cancer
  • Digestive system
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Immune system
  • Nervous system
  • Cardiovascular
Mechanism of action:
  • PPI modulators
Targets:
  • Kinases
  • Others
  • Ion Channels
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with M373-1548 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M373-1548?
Check Price and Availability of M373-1548, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M373-1548 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M373-1548
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M373-1548
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M373-1548 available by request