M381-2805 Screening compound: 2-(2-chloro-6-fluorophenyl)-N-[4-(pyrrolidin-1-yl)quinazolin-6-yl]acetamide

M381-2805 Screening compound: 2-(2-chloro-6-fluorophenyl)-N-[4-(pyrrolidin-1-yl)quinazolin-6-yl]acetamide
M381-2805 Screening compound: 2-(2-chloro-6-fluorophenyl)-N-[4-(pyrrolidin-1-yl)quinazolin-6-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M381-2805
2-(2-chloro-6-fluorophenyl)-N-[4-(pyrrolidin-1-yl)quinazolin-6-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M381-2805

Molecular Formula

C20H18ClFN4O (C20 H18 ClFN4 O)

Compound Name

2-(2-chloro-6-fluorophenyl)-N-[4-(pyrrolidin-1-yl)quinazolin-6-yl]acetamide

IUPAC name

2-(2-chloro-6-fluorophenyl)-N-[4-(pyrrolidin-1-yl)quinazolin-6-yl]acetamide

SMILES

O=C(Cc(c(F)ccc1)c1Cl)Nc1cc2c(N3CCCC3)ncnc2cc1

InChI

InChI=1S/C20H18ClFN4O/c21-16-4-3-5-17(22)14(16)11-19(27)25-13-6-7-18-15(10-13)20(24-12-23-18)26-8-1-2-9-26/h3-7,10,12H,1-2,8-9,11H2,(H,25,27)

InChI Key

OMJWFGALVGRIJS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27539813

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

384.84

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.524

Distribution Coefficient, logD

4.522

Water Solubility, LogSw

-4.51

Polar Surface Area

46.393

Acid Dissociation Constant (pKa)

11.28

Base Dissociation Constant (pKb)

5.12

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

M381-2805 in Drug Discovery

Included in Screening Libraries

Hsp90-Targeted Library (11355 compounds)

Ion Channels Focused Library (26372 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels
Agro:
  • Agro

References: we are preparing a list of scientific research reports with M381-2805 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M381-2805?
Check Price and Availability of M381-2805, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M381-2805 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M381-2805
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M381-2805
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M381-2805 available by request