M381-2966 Screening compound: N-[4-(piperidin-1-yl)quinazolin-6-yl]-2-(trifluoromethyl)benzamide
Chemical Structure Depiction of ChemDiv screening compound M381-2966
N-[4-(piperidin-1-yl)quinazolin-6-yl]-2-(trifluoromethyl)benzamide
Available from 1 mg
Formats:
- Glass Vials (4ml Glass Vials VWR #97047-678)
- 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)
Shiptime: 1 week worldwide delivery in most cases
Compound Identifiers
ChemDiv Compound ID
M381-2966
Molecular Formula
C21H19F3N4O (C21 H19 F3 N4 O)
Compound Name
N-[4-(piperidin-1-yl)quinazolin-6-yl]-2-(trifluoromethyl)benzamide
IUPAC name
N-[4-(piperidin-1-yl)quinazolin-6-yl]-2-(trifluoromethyl)benzamide
SMILES
O=C(c1c(C(F)(F)F)cccc1)Nc1cc2c(N3CCCCC3)ncnc2cc1
InChI Key
MDL Number (MFCD)
Chemical and Physical Properties
Saltdata
n/a
Molecular Weight
400.4
Hydrogen Bond Acceptors Count
4.00
Hydrogen Bond Donors Count
1.00
Rotatable Bond Count
5.00
Number of Nitrogen and Oxygen Atoms
5
Partition Coefficient, logP
4.617
Distribution Coefficient, logD
4.247
Water Solubility, LogSw
-4.30
Polar Surface Area
46.240
Acid Dissociation Constant (pKa)
7.27
Base Dissociation Constant (pKb)
5.12
Number of Chiral Centers
0.00
Percent sp3 carbon bonding
28.60
M381-2966 in Drug Discovery
Included in Screening Libraries
300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)
Hsp90-Targeted Library (11355 compounds)
Protein Kinases Inhibitors Library (36801 compounds)
Ion Channels Focused Library (26372 compounds)
Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)
Included in 1.7M Stock Database
- Nervous system
- Cancer
- Digestive system
- Respiratory tract
- Male
- Female
- Hemic and lymphatic
- Immune system
- Cancer
- Digestive system
- Respiratory tract
- Otorhinolaryngologic
- Nervous system
- Hemic and lymphatic
- Cardiovascular
- Nervous system
- Cardiovascular
- Cancer
- Nervous system
- Male
- Female
- Hemic and lymphatic
- Skin
- Endocrine
- Kinases
- Ion Channels
- Phosphatases
References: we are preparing a list of scientific research reports with M381-2966 chemical compound. It will be published here after verification.
Frequently Asked Questions
Check Price and Availability of M381-2966, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
Available from 1 mg in Glass Vials or 96-tube racks.
ChemDiv sends parcels with Express services (UPS, WC).
- 1–2 days for small orders
- 2–4 weeks for large selections
- 0.5–50 mg of dry powder sample in single glass vials, custom vials
- DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)