M381-3009 Screening compound: 1-phenyl-N~1~-(4-piperidino-6-quinazolinyl)-1-cyclopropanecarboxamide

M381-3009 Screening compound: 1-phenyl-N~1~-(4-piperidino-6-quinazolinyl)-1-cyclopropanecarboxamide
M381-3009 Screening compound: 1-phenyl-N~1~-(4-piperidino-6-quinazolinyl)-1-cyclopropanecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M381-3009
1-phenyl-N~1~-(4-piperidino-6-quinazolinyl)-1-cyclopropanecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M381-3009

Molecular Formula

C23H24N4O (C23 H24 N4 O)

Compound Name

1-phenyl-N~1~-(4-piperidino-6-quinazolinyl)-1-cyclopropanecarboxamide

IUPAC name

1-phenyl-N-[4-(piperidin-1-yl)quinazolin-6-yl]cyclopropane-1-carboxamide

SMILES

O=C(C1(CC1)c1ccccc1)Nc1cc2c(N3CCCCC3)ncnc2cc1

InChI

InChI=1S/C23H24N4O/c28-22(23(11-12-23)17-7-3-1-4-8-17)26-18-9-10-20-19(15-18)21(25-16-24-20)27-13-5-2-6-14-27/h1,3-4,7-10,15-16H,2,5-6,11-14H2,(H,26,28)

InChI Key

BFZGWMNLVSQTSJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27539891

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

372.47

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.607

Distribution Coefficient, logD

4.605

Water Solubility, LogSw

-4.34

Polar Surface Area

46.492

Acid Dissociation Constant (pKa)

11.03

Base Dissociation Constant (pKb)

5.12

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.78

M381-3009 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

Hsp90-Targeted Library (11355 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Hemic and lymphatic
  • Cardiovascular

References: we are preparing a list of scientific research reports with M381-3009 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M381-3009?
Check Price and Availability of M381-3009, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M381-3009 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M381-3009
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M381-3009
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M381-3009 available by request