M422-0094 Screening compound: 5-(piperidine-1-carbonyl)-3-(pyridin-2-yl)-1,2-thiazol-4-amine

M422-0094 Screening compound: 5-(piperidine-1-carbonyl)-3-(pyridin-2-yl)-1,2-thiazol-4-amine
M422-0094 Screening compound: 5-(piperidine-1-carbonyl)-3-(pyridin-2-yl)-1,2-thiazol-4-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound M422-0094
5-(piperidine-1-carbonyl)-3-(pyridin-2-yl)-1,2-thiazol-4-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M422-0094

Molecular Formula

C14H16N4OS (C14 H16 N4 OS)

Compound Name

5-(piperidine-1-carbonyl)-3-(pyridin-2-yl)-1,2-thiazol-4-amine

IUPAC name

5-(piperidine-1-carbonyl)-3-(pyridin-2-yl)-12-thiazol-4-amine

SMILES

Nc1c(C(N2CCCCC2)=O)snc1-c1ncccc1

InChI

InChI=1S/C14H16N4OS/c15-11-12(10-6-2-3-7-16-10)17-20-13(11)14(19)18-8-4-1-5-9-18/h2-3,6-7H,1,4-5,8-9,15H2

InChI Key

PKJBCTFEXDMNQL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27540820

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

288.37

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

1.889

Distribution Coefficient, logD

1.889

Water Solubility, LogSw

-2.15

Polar Surface Area

56.311

Acid Dissociation Constant (pKa)

18.68

Base Dissociation Constant (pKb)

4.00

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

35.70

M422-0094 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Ion Channels Focused Library (26372 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cardiovascular
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Ion Channels
  • Phosphatases

References: we are preparing a list of scientific research reports with M422-0094 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M422-0094?
Check Price and Availability of M422-0094, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M422-0094 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M422-0094
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M422-0094
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M422-0094 available by request