M425-0271 Screening compound: N-[(2-chlorophenyl)methyl]-6-oxo-1-({[4-(propan-2-yl)phenyl]carbamoyl}methyl)-1,6-dihydropyridine-2-carboxamide

M425-0271 Screening compound: N-[(2-chlorophenyl)methyl]-6-oxo-1-({[4-(propan-2-yl)phenyl]carbamoyl}methyl)-1,6-dihydropyridine-2-carboxamide
M425-0271 Screening compound: N-[(2-chlorophenyl)methyl]-6-oxo-1-({[4-(propan-2-yl)phenyl]carbamoyl}methyl)-1,6-dihydropyridine-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M425-0271
N-[(2-chlorophenyl)methyl]-6-oxo-1-({[4-(propan-2-yl)phenyl]carbamoyl}methyl)-1,6-dihydropyridine-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M425-0271

Molecular Formula

C24H24ClN3O3 (C24 H24 ClN3 O3)

Compound Name

N-[(2-chlorophenyl)methyl]-6-oxo-1-({[4-(propan-2-yl)phenyl]carbamoyl}methyl)-1,6-dihydropyridine-2-carboxamide

IUPAC name

N-[(2-chlorophenyl)methyl]-6-oxo-1-({[4-(propan-2-yl)phenyl]carbamoyl}methyl)-16-dihydropyridine-2-carboxamide

SMILES

CC(C)c(cc1)ccc1NC(CN1C(C(NCc(cccc2)c2Cl)=O)=CC=CC1=O)=O

InChI

InChI=1S/C24H24ClN3O3/c1-16(2)17-10-12-19(13-11-17)27-22(29)15-28-21(8-5-9-23(28)30)24(31)26-14-18-6-3-4-7-20(18)25/h3-13,16H,14-15H2,1-2H3,(H,26,31)(H,27,29)

InChI Key

OUBNKUOWQQZPJJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27541011

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

437.93

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.581

Distribution Coefficient, logD

4.505

Water Solubility, LogSw

-4.66

Polar Surface Area

63.676

Acid Dissociation Constant (pKa)

8.12

Base Dissociation Constant (pKb)

-0.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.80

M425-0271 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with M425-0271 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M425-0271?
Check Price and Availability of M425-0271, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M425-0271 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M425-0271
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M425-0271
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M425-0271 available by request