M428-1497 Screening compound: N-CYCLOPROPYL-1-[6-(ETHYLSULFANYL)-3-PYRIDAZINYL]-5-METHYL-1H-PYRAZOLE-4-CARBOXAMIDE

M428-1497 Screening compound: N-CYCLOPROPYL-1-[6-(ETHYLSULFANYL)-3-PYRIDAZINYL]-5-METHYL-1H-PYRAZOLE-4-CARBOXAMIDE
M428-1497 Screening compound: N-CYCLOPROPYL-1-[6-(ETHYLSULFANYL)-3-PYRIDAZINYL]-5-METHYL-1H-PYRAZOLE-4-CARBOXAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound M428-1497
N-CYCLOPROPYL-1-[6-(ETHYLSULFANYL)-3-PYRIDAZINYL]-5-METHYL-1H-PYRAZOLE-4-CARBOXAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M428-1497

Molecular Formula

C14H17N5OS (C14 H17 N5 OS)

Compound Name

N-CYCLOPROPYL-1-[6-(ETHYLSULFANYL)-3-PYRIDAZINYL]-5-METHYL-1H-PYRAZOLE-4-CARBOXAMIDE

IUPAC name

N-cyclopropyl-1-[6-(ethylsulfanyl)pyridazin-3-yl]-5-methyl-1H-pyrazole-4-carboxamide

SMILES

CCSc(cc1)nnc1-n1ncc(C(NC2CC2)=O)c1C

InChI

InChI=1S/C14H17N5OS/c1-3-21-13-7-6-12(17-18-13)19-9(2)11(8-15-19)14(20)16-10-4-5-10/h6-8,10H,3-5H2,1-2H3,(H,16,20)

InChI Key

PBIOPPHBLACDRJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27541265

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

303.39

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.298

Distribution Coefficient, logD

2.298

Water Solubility, LogSw

-2.79

Polar Surface Area

59.341

Acid Dissociation Constant (pKa)

12.47

Base Dissociation Constant (pKb)

2.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.86

M428-1497 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

GPCR Targeted Library (31838 compounds)

Soluble Diversity Library (15920 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with M428-1497 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M428-1497?
Check Price and Availability of M428-1497, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M428-1497 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M428-1497
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M428-1497
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M428-1497 available by request