M460-3856 Screening compound: 2-[8-(morpholin-4-yl)-3-oxo-2H,3H-[1,2,4]triazolo[4,3-a]pyrazin-2-yl]-N-[2-(4-sulfamoylphenyl)ethyl]acetamide

M460-3856 Screening compound: 2-[8-(morpholin-4-yl)-3-oxo-2H,3H-[1,2,4]triazolo[4,3-a]pyrazin-2-yl]-N-[2-(4-sulfamoylphenyl)ethyl]acetamide
M460-3856 Screening compound: 2-[8-(morpholin-4-yl)-3-oxo-2H,3H-[1,2,4]triazolo[4,3-a]pyrazin-2-yl]-N-[2-(4-sulfamoylphenyl)ethyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M460-3856
2-[8-(morpholin-4-yl)-3-oxo-2H,3H-[1,2,4]triazolo[4,3-a]pyrazin-2-yl]-N-[2-(4-sulfamoylphenyl)ethyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M460-3856

Molecular Formula

C19H23N7O5S (C19 H23 N7 O5 S)

Compound Name

2-[8-(morpholin-4-yl)-3-oxo-2H,3H-[1,2,4]triazolo[4,3-a]pyrazin-2-yl]-N-[2-(4-sulfamoylphenyl)ethyl]acetamide

IUPAC name

2-[8-(morpholin-4-yl)-3-oxo-2H3H-[124]triazolo[43-a]pyrazin-2-yl]-N-[2-(4-sulfamoylphenyl)ethyl]acetamide

SMILES

NS(c1ccc(CCNC(CN2N=C(C(N3CCOCC3)=NC=C3)N3C2=O)=O)cc1)(=O)=O

InChI

InChI=1S/C19H23N7O5S/c20-32(29,30)15-3-1-14(2-4-15)5-6-21-16(27)13-26-19(28)25-8-7-22-17(18(25)23-26)24-9-11-31-12-10-24/h1-4,7-8H,5-6,9-13H2,(H,21,27)(H2,20,29,30)

InChI Key

PZUKIHYXOMWKCQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27542899

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

461.5

Hydrogen Bond Acceptors Count

12.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

12

Partition Coefficient, logP

-1.791

Distribution Coefficient, logD

-1.792

Water Solubility, LogSw

-1.95

Polar Surface Area

124.884

Acid Dissociation Constant (pKa)

10.18

Base Dissociation Constant (pKb)

-0.27

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.80

M460-3856 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Akt-Targeted Library (14764 compounds)

SH2 PTB Focused Library (6188 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • Receptor's ligands
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • GPCR
  • Kinases

References: we are preparing a list of scientific research reports with M460-3856 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M460-3856?
Check Price and Availability of M460-3856, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M460-3856 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M460-3856
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M460-3856
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M460-3856 available by request