M461-5437 Screening compound: 2-[(3-{[4-(2-ethoxyphenyl)piperazin-1-yl]sulfonyl}-1-ethyl-1H-pyrazol-4-yl)formamido]acetamide

M461-5437 Screening compound: 2-[(3-{[4-(2-ethoxyphenyl)piperazin-1-yl]sulfonyl}-1-ethyl-1H-pyrazol-4-yl)formamido]acetamide
M461-5437 Screening compound: 2-[(3-{[4-(2-ethoxyphenyl)piperazin-1-yl]sulfonyl}-1-ethyl-1H-pyrazol-4-yl)formamido]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M461-5437
2-[(3-{[4-(2-ethoxyphenyl)piperazin-1-yl]sulfonyl}-1-ethyl-1H-pyrazol-4-yl)formamido]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M461-5437

Molecular Formula

C20H28N6O5S (C20 H28 N6 O5 S)

Compound Name

2-[(3-{[4-(2-ethoxyphenyl)piperazin-1-yl]sulfonyl}-1-ethyl-1H-pyrazol-4-yl)formamido]acetamide

IUPAC name

2-[(3-{[4-(2-ethoxyphenyl)piperazin-1-yl]sulfonyl}-1-ethyl-1H-pyrazol-4-yl)formamido]acetamide

SMILES

CCn(cc1C(NCC(N)=O)=O)nc1S(N(CC1)CCN1c(cccc1)c1OCC)(=O)=O

InChI

InChI=1S/C20H28N6O5S/c1-3-25-14-15(19(28)22-13-18(21)27)20(23-25)32(29,30)26-11-9-24(10-12-26)16-7-5-6-8-17(16)31-4-2/h5-8,14H,3-4,9-13H2,1-2H3,(H2,21,27)(H,22,28)

InChI Key

SNJSKBMFEHCFOK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27543180

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

464.55

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

11

Partition Coefficient, logP

0.844

Distribution Coefficient, logD

0.844

Water Solubility, LogSw

-2.44

Polar Surface Area

115.015

Acid Dissociation Constant (pKa)

12.21

Base Dissociation Constant (pKb)

5.18

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

45.00

M461-5437 in Drug Discovery

Included in Screening Libraries

Adenosine Receptors Targeted Library (19896 compounds)

SH2 PTB Focused Library (6188 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with M461-5437 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M461-5437?
Check Price and Availability of M461-5437, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M461-5437 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M461-5437
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M461-5437
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M461-5437 available by request