M466-1277 Screening compound: N-[3-(5-methylthiophen-2-yl)-1,2-oxazol-5-yl]-2-(thiophen-3-yl)acetamide

M466-1277 Screening compound: N-[3-(5-methylthiophen-2-yl)-1,2-oxazol-5-yl]-2-(thiophen-3-yl)acetamide
M466-1277 Screening compound: N-[3-(5-methylthiophen-2-yl)-1,2-oxazol-5-yl]-2-(thiophen-3-yl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M466-1277
N-[3-(5-methylthiophen-2-yl)-1,2-oxazol-5-yl]-2-(thiophen-3-yl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M466-1277

Molecular Formula

C14H12N2O2S2 (C14 H12 N2 O2 S2)

Compound Name

N-[3-(5-methylthiophen-2-yl)-1,2-oxazol-5-yl]-2-(thiophen-3-yl)acetamide

IUPAC name

N-[3-(5-methylthiophen-2-yl)-12-oxazol-5-yl]-2-(thiophen-3-yl)acetamide

SMILES

Cc1ccc(-c2noc(NC(Cc3cscc3)=O)c2)s1

InChI

InChI=1S/C14H12N2O2S2/c1-9-2-3-12(20-9)11-7-14(18-16-11)15-13(17)6-10-4-5-19-8-10/h2-5,7-8H,6H2,1H3,(H,15,17)

InChI Key

ZHHDTCFOBVEHNF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27543792

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

304.39

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.611

Distribution Coefficient, logD

3.610

Water Solubility, LogSw

-3.73

Polar Surface Area

47.434

Acid Dissociation Constant (pKa)

10.18

Base Dissociation Constant (pKb)

-5.08

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

14.30

M466-1277 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Others
  • Kinases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with M466-1277 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M466-1277?
Check Price and Availability of M466-1277, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M466-1277 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M466-1277
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M466-1277
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M466-1277 available by request