M477-0658 Screening compound: N~1~-[2-(3-isopropyl-3H-imidazo[4,5-b]pyridin-2-yl)ethyl]-1-phenyl-1-cyclopropanecarboxamide

M477-0658 Screening compound: N~1~-[2-(3-isopropyl-3H-imidazo[4,5-b]pyridin-2-yl)ethyl]-1-phenyl-1-cyclopropanecarboxamide
M477-0658 Screening compound: N~1~-[2-(3-isopropyl-3H-imidazo[4,5-b]pyridin-2-yl)ethyl]-1-phenyl-1-cyclopropanecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M477-0658
N~1~-[2-(3-isopropyl-3H-imidazo[4,5-b]pyridin-2-yl)ethyl]-1-phenyl-1-cyclopropanecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M477-0658

Molecular Formula

C21H24N4O (C21 H24 N4 O)

Compound Name

N~1~-[2-(3-isopropyl-3H-imidazo[4,5-b]pyridin-2-yl)ethyl]-1-phenyl-1-cyclopropanecarboxamide

IUPAC name

n/a

SMILES

CC(C)n1c(nccc2)c2nc1CCNC(C1(CC1)c1ccccc1)=O

InChI

InChI=1S/C21H24N4O/c1-15(2)25-18(24-17-9-6-13-22-19(17)25)10-14-23-20(26)21(11-12-21)16-7-4-3-5-8-16/h3-9,13,15H,10-12,14H2,1-2H3,(H,23,26)

InChI Key

DKGOKDDENZGFSN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27544342

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

348.45

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.626

Distribution Coefficient, logD

2.626

Water Solubility, LogSw

-2.94

Polar Surface Area

46.903

Acid Dissociation Constant (pKa)

13.91

Base Dissociation Constant (pKb)

3.43

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.10

M477-0658 in Drug Discovery

Included in Screening Libraries

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with M477-0658 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M477-0658?
Check Price and Availability of M477-0658, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M477-0658 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M477-0658
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M477-0658
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M477-0658 available by request