M543-0078 Screening compound: 1-acetyl-5-methyl-N-[(oxolan-2-yl)methyl]-2,3-dihydro-1H-indole-6-sulfonamide

M543-0078 Screening compound: 1-acetyl-5-methyl-N-[(oxolan-2-yl)methyl]-2,3-dihydro-1H-indole-6-sulfonamide
M543-0078 Screening compound: 1-acetyl-5-methyl-N-[(oxolan-2-yl)methyl]-2,3-dihydro-1H-indole-6-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M543-0078
1-acetyl-5-methyl-N-[(oxolan-2-yl)methyl]-2,3-dihydro-1H-indole-6-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M543-0078

Molecular Formula

C16H22N2O4S (C16 H22 N2 O4 S)

Compound Name

1-acetyl-5-methyl-N-[(oxolan-2-yl)methyl]-2,3-dihydro-1H-indole-6-sulfonamide

IUPAC name

1-acetyl-5-methyl-N-[(oxolan-2-yl)methyl]-23-dihydro-1H-indole-6-sulfonamide

SMILES

CC(N1c2cc(S(NCC3OCCC3)(=O)=O)c(C)cc2CC1)=O

InChI

InChI=1S/C16H22N2O4S/c1-11-8-13-5-6-18(12(2)19)15(13)9-16(11)23(20,21)17-10-14-4-3-7-22-14/h8-9,14,17H,3-7,10H2,1-2H3/t14-/m1/s1

InChI Key

BSDVADUJDSDODG-CQSZACIVSA-N

MDL Number (MFCD)

MFCD27546794

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

338.43

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

1.342

Distribution Coefficient, logD

1.342

Water Solubility, LogSw

-2.21

Polar Surface Area

67.069

Acid Dissociation Constant (pKa)

10.99

Base Dissociation Constant (pKb)

1.91

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

56.30

M543-0078 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

SmartTM Library (51161 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators

References: we are preparing a list of scientific research reports with M543-0078 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M543-0078?
Check Price and Availability of M543-0078, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M543-0078 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M543-0078
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M543-0078
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M543-0078 available by request