M735-1454 Screening compound: (2-{[1-(1,4-dioxaspiro[4.5]dec-8-yl)-3-piperidyl]methoxy}phenyl)(morpholino)methanone

M735-1454 Screening compound: (2-{[1-(1,4-dioxaspiro[4.5]dec-8-yl)-3-piperidyl]methoxy}phenyl)(morpholino)methanone
M735-1454 Screening compound: (2-{[1-(1,4-dioxaspiro[4.5]dec-8-yl)-3-piperidyl]methoxy}phenyl)(morpholino)methanone alternative view

Chemical Structure Depiction of ChemDiv screening compound M735-1454
(2-{[1-(1,4-dioxaspiro[4.5]dec-8-yl)-3-piperidyl]methoxy}phenyl)(morpholino)methanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M735-1454

Molecular Formula

C25H36N2O5 (C25 H36 N2 O5)

Compound Name

(2-{[1-(1,4-dioxaspiro[4.5]dec-8-yl)-3-piperidyl]methoxy}phenyl)(morpholino)methanone

IUPAC name

4-{2-[(1-{14-dioxaspiro[4.5]decan-8-yl}piperidin-3-yl)methoxy]benzoyl}morpholine

SMILES

O=C(c(cccc1)c1OCC(CCC1)CN1C(CC1)CCC11OCCO1)N1CCOCC1

InChI

InChI=1S/C25H36N2O5/c28-24(26-12-14-29-15-13-26)22-5-1-2-6-23(22)30-19-20-4-3-11-27(18-20)21-7-9-25(10-8-21)31-16-17-32-25/h1-2,5-6,20-21H,3-4,7-19H2/t20-/m0/s1

InChI Key

FSGNNLHVWTWLHR-FQEVSTJZSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

444.57

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.402

Distribution Coefficient, logD

-0.091

Water Solubility, LogSw

-2.77

Polar Surface Area

49.765

Acid Dissociation Constant (pKa)

25.52

Base Dissociation Constant (pKb)

9.89

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

72.00

M735-1454 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Eccentric PPI Library (11937 compounds)

GPCR Targeted Library (31838 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • Receptor's ligands
  • PPI modulators
Structure:
  • Cyclic compounds
Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR

References: we are preparing a list of scientific research reports with M735-1454 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M735-1454?
Check Price and Availability of M735-1454, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M735-1454 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M735-1454
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M735-1454
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M735-1454 available by request