M892-1872 Screening compound: 2-{5-[(3-methylphenyl)amino]-1,3,4-thiadiazol-2-yl}-N-(4-phenylbutan-2-yl)acetamide

M892-1872 Screening compound: 2-{5-[(3-methylphenyl)amino]-1,3,4-thiadiazol-2-yl}-N-(4-phenylbutan-2-yl)acetamide
M892-1872 Screening compound: 2-{5-[(3-methylphenyl)amino]-1,3,4-thiadiazol-2-yl}-N-(4-phenylbutan-2-yl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M892-1872
2-{5-[(3-methylphenyl)amino]-1,3,4-thiadiazol-2-yl}-N-(4-phenylbutan-2-yl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M892-1872

Molecular Formula

C21H24N4OS (C21 H24 N4 OS)

Compound Name

2-{5-[(3-methylphenyl)amino]-1,3,4-thiadiazol-2-yl}-N-(4-phenylbutan-2-yl)acetamide

IUPAC name

2-{5-[(3-methylphenyl)amino]-134-thiadiazol-2-yl}-N-(4-phenylbutan-2-yl)acetamide

SMILES

CC(CCc1ccccc1)NC(Cc1nnc(Nc2cc(C)ccc2)s1)=O

InChI

InChI=1S/C21H24N4OS/c1-15-7-6-10-18(13-15)23-21-25-24-20(27-21)14-19(26)22-16(2)11-12-17-8-4-3-5-9-17/h3-10,13,16H,11-12,14H2,1-2H3,(H,22,26)(H,23,25)/t16-/m0/s1

InChI Key

NMZMFONBRRUJQD-INIZCTEOSA-N

MDL Number (MFCD)

MFCD27556474

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

380.51

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.746

Distribution Coefficient, logD

4.746

Water Solubility, LogSw

-4.54

Polar Surface Area

56.832

Acid Dissociation Constant (pKa)

15.23

Base Dissociation Constant (pKb)

4.77

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

28.60

M892-1872 in Drug Discovery

Included in Screening Libraries

Glucocorticoid receptors Library (4806 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Nuclear receptors
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with M892-1872 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M892-1872?
Check Price and Availability of M892-1872, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M892-1872 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M892-1872
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M892-1872
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M892-1872 available by request