P038-4440 Screening compound: N-(4-ethoxyphenyl)-1-(4-fluorophenyl)-3-methyl-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-6-carboxamide

P038-4440 Screening compound: N-(4-ethoxyphenyl)-1-(4-fluorophenyl)-3-methyl-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-6-carboxamide
P038-4440 Screening compound: N-(4-ethoxyphenyl)-1-(4-fluorophenyl)-3-methyl-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-6-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P038-4440
N-(4-ethoxyphenyl)-1-(4-fluorophenyl)-3-methyl-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-6-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P038-4440

Molecular Formula

C23H19FN4O4 (C23 H19 FN4 O4)

Compound Name

N-(4-ethoxyphenyl)-1-(4-fluorophenyl)-3-methyl-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-6-carboxamide

IUPAC name

N-(4-ethoxyphenyl)-1-(4-fluorophenyl)-3-methyl-24-dioxo-1H2H3H4H-pyrido[23-d]pyrimidine-6-carboxamide

SMILES

CCOc(cc1)ccc1NC(c(cc1C(N2C)=O)cnc1N(c(cc1)ccc1F)C2=O)=O

InChI

InChI=1S/C23H19FN4O4/c1-3-32-18-10-6-16(7-11-18)26-21(29)14-12-19-20(25-13-14)28(23(31)27(2)22(19)30)17-8-4-15(24)5-9-17/h4-13H,3H2,1-2H3,(H,26,29)

InChI Key

KUDIHQSTWFGCIL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27559780

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

434.43

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.501

Distribution Coefficient, logD

3.497

Water Solubility, LogSw

-3.70

Polar Surface Area

71.328

Acid Dissociation Constant (pKa)

9.43

Base Dissociation Constant (pKb)

0.33

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.00

P038-4440 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Hsp90-Targeted Library (11355 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system

References: we are preparing a list of scientific research reports with P038-4440 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P038-4440?
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What is the minimum amount of P038-4440 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P038-4440
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P038-4440
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P038-4440 available by request