P055-2152 Screening compound: {4-[4-(morpholinomethyl)-1,3-thiazol-2-yl]piperazino}(2-pyridyl)methanone

P055-2152 Screening compound: {4-[4-(morpholinomethyl)-1,3-thiazol-2-yl]piperazino}(2-pyridyl)methanone
P055-2152 Screening compound: {4-[4-(morpholinomethyl)-1,3-thiazol-2-yl]piperazino}(2-pyridyl)methanone alternative view

Chemical Structure Depiction of ChemDiv screening compound P055-2152
{4-[4-(morpholinomethyl)-1,3-thiazol-2-yl]piperazino}(2-pyridyl)methanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P055-2152

Molecular Formula

C18H23N5O2S (C18 H23 N5 O2 S)

Compound Name

{4-[4-(morpholinomethyl)-1,3-thiazol-2-yl]piperazino}(2-pyridyl)methanone

IUPAC name

4-({2-[4-(pyridine-2-carbonyl)piperazin-1-yl]-13-thiazol-4-yl}methyl)morpholine

SMILES

O=C(c1ncccc1)N(CC1)CCN1c1nc(CN2CCOCC2)cs1

InChI

InChI=1S/C18H23N5O2S/c24-17(16-3-1-2-4-19-16)22-5-7-23(8-6-22)18-20-15(14-26-18)13-21-9-11-25-12-10-21/h1-4,14H,5-13H2

InChI Key

BGJUDVWXSZFGHS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27561188

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

373.48

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.306

Distribution Coefficient, logD

1.012

Water Solubility, LogSw

-2.03

Polar Surface Area

51.152

Acid Dissociation Constant (pKa)

23.58

Base Dissociation Constant (pKb)

7.39

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

P055-2152 in Drug Discovery

Included in Screening Libraries

Antiviral HBV Library (10007 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

PI3K-Targeted Library (17255 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • GPCR
  • Kinases
  • Proteases
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with P055-2152 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P055-2152?
Check Price and Availability of P055-2152, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P055-2152 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P055-2152
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P055-2152
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P055-2152 available by request