P086-1636 Screening compound: 2-(3-methoxyphenyl)-1-[2-(5-tetrahydro-2H-pyran-4-yl-1,3,4-oxadiazol-2-yl)-2,3-dihydro-1H-indol-1-yl]-1-ethanone

P086-1636 Screening compound: 2-(3-methoxyphenyl)-1-[2-(5-tetrahydro-2H-pyran-4-yl-1,3,4-oxadiazol-2-yl)-2,3-dihydro-1H-indol-1-yl]-1-ethanone
P086-1636 Screening compound: 2-(3-methoxyphenyl)-1-[2-(5-tetrahydro-2H-pyran-4-yl-1,3,4-oxadiazol-2-yl)-2,3-dihydro-1H-indol-1-yl]-1-ethanone alternative view

Chemical Structure Depiction of ChemDiv screening compound P086-1636
2-(3-methoxyphenyl)-1-[2-(5-tetrahydro-2H-pyran-4-yl-1,3,4-oxadiazol-2-yl)-2,3-dihydro-1H-indol-1-yl]-1-ethanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P086-1636

Molecular Formula

C24H25N3O4 (C24 H25 N3 O4)

Compound Name

2-(3-methoxyphenyl)-1-[2-(5-tetrahydro-2H-pyran-4-yl-1,3,4-oxadiazol-2-yl)-2,3-dihydro-1H-indol-1-yl]-1-ethanone

IUPAC name

2-(3-methoxyphenyl)-1-{2-[5-(oxan-4-yl)-134-oxadiazol-2-yl]-23-dihydro-1H-indol-1-yl}ethan-1-one

SMILES

COc1cccc(CC(N(C(C2)c3nnc(C4CCOCC4)o3)c3c2cccc3)=O)c1

InChI

InChI=1S/C24H25N3O4/c1-29-19-7-4-5-16(13-19)14-22(28)27-20-8-3-2-6-18(20)15-21(27)24-26-25-23(31-24)17-9-11-30-12-10-17/h2-8,13,17,21H,9-12,14-15H2,1H3/t21-/m0/s1

InChI Key

JIIMIEXLZWMTAD-NRFANRHFSA-N

MDL Number (MFCD)

MFCD29002173

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

419.48

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.711

Distribution Coefficient, logD

3.711

Water Solubility, LogSw

-4.06

Polar Surface Area

60.626

Acid Dissociation Constant (pKa)

16.37

Base Dissociation Constant (pKb)

-2.72

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

37.50

P086-1636 in Drug Discovery

Included in Screening Libraries

Indole Derivatives (10091 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Structure:
  • Cyclic compounds
  • Cyclic compounds
Mechanism of action:
  • PPI modulators
  • PPI modulators
Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with P086-1636 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P086-1636?
Check Price and Availability of P086-1636, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P086-1636 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P086-1636
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P086-1636
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P086-1636 available by request