P086-1772 Screening compound: (1-ethyl-1H-pyrazol-5-yl)[2-(5-tetrahydro-2H-pyran-4-yl-1,3,4-oxadiazol-2-yl)-2,3-dihydro-1H-indol-1-yl]methanone

P086-1772 Screening compound: (1-ethyl-1H-pyrazol-5-yl)[2-(5-tetrahydro-2H-pyran-4-yl-1,3,4-oxadiazol-2-yl)-2,3-dihydro-1H-indol-1-yl]methanone
P086-1772 Screening compound: (1-ethyl-1H-pyrazol-5-yl)[2-(5-tetrahydro-2H-pyran-4-yl-1,3,4-oxadiazol-2-yl)-2,3-dihydro-1H-indol-1-yl]methanone alternative view

Chemical Structure Depiction of ChemDiv screening compound P086-1772
(1-ethyl-1H-pyrazol-5-yl)[2-(5-tetrahydro-2H-pyran-4-yl-1,3,4-oxadiazol-2-yl)-2,3-dihydro-1H-indol-1-yl]methanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P086-1772

Molecular Formula

C21H23N5O3 (C21 H23 N5 O3)

Compound Name

(1-ethyl-1H-pyrazol-5-yl)[2-(5-tetrahydro-2H-pyran-4-yl-1,3,4-oxadiazol-2-yl)-2,3-dihydro-1H-indol-1-yl]methanone

IUPAC name

n/a

SMILES

CCn1nccc1C(N(C(C1)c2nnc(C3CCOCC3)o2)c2c1cccc2)=O

InChI

InChI=1S/C21H23N5O3/c1-2-25-17(7-10-22-25)21(27)26-16-6-4-3-5-15(16)13-18(26)20-24-23-19(29-20)14-8-11-28-12-9-14/h3-7,10,14,18H,2,8-9,11-13H2,1H3/t18-/m0/s1

InChI Key

LAEDPKPKYCWRKU-SFHVURJKSA-N

MDL Number (MFCD)

MFCD29005673

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

393.45

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.290

Distribution Coefficient, logD

2.290

Water Solubility, LogSw

-2.44

Polar Surface Area

66.699

Acid Dissociation Constant (pKa)

25.64

Base Dissociation Constant (pKb)

-0.26

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

42.90

P086-1772 in Drug Discovery

Included in Screening Libraries

Antifungal Library (16415 compounds)

Indole Derivatives (10091 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Cancer
Agro:
  • Agro
Structure:
  • Cyclic compounds
  • Cyclic compounds
Mechanism of action:
  • PPI modulators
  • PPI modulators

References: we are preparing a list of scientific research reports with P086-1772 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P086-1772?
Check Price and Availability of P086-1772, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P086-1772 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P086-1772
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P086-1772
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P086-1772 available by request