P169-2274 Screening compound: N-({2-ethyl-6-phenylimidazo[2,1-b][1,3,4]thiadiazol-5-yl}methyl)-4-(trifluoromethoxy)benzamide

P169-2274 Screening compound: N-({2-ethyl-6-phenylimidazo[2,1-b][1,3,4]thiadiazol-5-yl}methyl)-4-(trifluoromethoxy)benzamide
P169-2274 Screening compound: N-({2-ethyl-6-phenylimidazo[2,1-b][1,3,4]thiadiazol-5-yl}methyl)-4-(trifluoromethoxy)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P169-2274
N-({2-ethyl-6-phenylimidazo[2,1-b][1,3,4]thiadiazol-5-yl}methyl)-4-(trifluoromethoxy)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P169-2274

Molecular Formula

C21H17F3N4O2S (C21 H17 F3 N4 O2 S)

Compound Name

N-({2-ethyl-6-phenylimidazo[2,1-b][1,3,4]thiadiazol-5-yl}methyl)-4-(trifluoromethoxy)benzamide

IUPAC name

N-({2-ethyl-6-phenylimidazo[21-b][134]thiadiazol-5-yl}methyl)-4-(trifluoromethoxy)benzamide

SMILES

CCc(s1)nn2c1nc(-c1ccccc1)c2CNC(c(cc1)ccc1OC(F)(F)F)=O

InChI

InChI=1S/C21H17F3N4O2S/c1-2-17-27-28-16(18(26-20(28)31-17)13-6-4-3-5-7-13)12-25-19(29)14-8-10-15(11-9-14)30-21(22,23)24/h3-11H,2,12H2,1H3,(H,25,29)

InChI Key

JGFMCVGTUBPMDF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27567933

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

446.45

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.097

Distribution Coefficient, logD

5.097

Water Solubility, LogSw

-4.94

Polar Surface Area

51.866

Acid Dissociation Constant (pKa)

11.46

Base Dissociation Constant (pKb)

0.18

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

19.00

P169-2274 in Drug Discovery

Included in Screening Libraries

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with P169-2274 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P169-2274?
Check Price and Availability of P169-2274, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P169-2274 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P169-2274
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P169-2274
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P169-2274 available by request