P223-1431 Screening compound: 5-methyl-2-(piperidin-3-yl)-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,4]diazepin-4-one

P223-1431 Screening compound: 5-methyl-2-(piperidin-3-yl)-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,4]diazepin-4-one
P223-1431 Screening compound: 5-methyl-2-(piperidin-3-yl)-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,4]diazepin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound P223-1431
5-methyl-2-(piperidin-3-yl)-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,4]diazepin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P223-1431

Molecular Formula

C13H20N4O (C13 H20 N4 O)

Compound Name

5-methyl-2-(piperidin-3-yl)-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,4]diazepin-4-one

IUPAC name

5-methyl-2-(piperidin-3-yl)-4H5H6H7H8H-pyrazolo[15-a][14]diazepin-4-one

SMILES

CN(CCCn1nc(C2CNCCC2)cc11)C1=O

InChI

InChI=1S/C13H20N4O/c1-16-6-3-7-17-12(13(16)18)8-11(15-17)10-4-2-5-14-9-10/h8,10,14H,2-7,9H2,1H3/t10-/m0/s1

InChI Key

AYPGATGNKXADBY-JTQLQIEISA-N

MDL Number (MFCD)

MFCD32224140

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

248.33

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

1.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

-0.663

Distribution Coefficient, logD

-4.362

Water Solubility, LogSw

-0.89

Polar Surface Area

42.181

Acid Dissociation Constant (pKa)

26.69

Base Dissociation Constant (pKb)

11.10

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

69.23

P223-1431 in Drug Discovery

Included in Screening Libraries

3D-Fragment Library (4274 compounds)

CNS BBB Library (22607 compounds)

CNS MPO Library (28609 compounds)

Soluble Diversity Library (15920 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Fragments
Therapeutical areas:
  • Nervous system
  • Nervous system
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with P223-1431 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P223-1431?
Check Price and Availability of P223-1431, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P223-1431 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P223-1431
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P223-1431
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P223-1431 available by request