P244-0156 Screening compound: 7-[2-(4-cyclohexylpiperazin-1-yl)-2-oxoethyl]-6-phenyl-5H,6H,7H-pyrrolo[3,4-b]pyridin-5-one

P244-0156 Screening compound: 7-[2-(4-cyclohexylpiperazin-1-yl)-2-oxoethyl]-6-phenyl-5H,6H,7H-pyrrolo[3,4-b]pyridin-5-one
P244-0156 Screening compound: 7-[2-(4-cyclohexylpiperazin-1-yl)-2-oxoethyl]-6-phenyl-5H,6H,7H-pyrrolo[3,4-b]pyridin-5-one alternative view

Chemical Structure Depiction of ChemDiv screening compound P244-0156
7-[2-(4-cyclohexylpiperazin-1-yl)-2-oxoethyl]-6-phenyl-5H,6H,7H-pyrrolo[3,4-b]pyridin-5-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P244-0156

Molecular Formula

C25H30N4O2 (C25 H30 N4 O2)

Compound Name

7-[2-(4-cyclohexylpiperazin-1-yl)-2-oxoethyl]-6-phenyl-5H,6H,7H-pyrrolo[3,4-b]pyridin-5-one

IUPAC name

7-[2-(4-cyclohexylpiperazin-1-yl)-2-oxoethyl]-6-phenyl-5H6H7H-pyrrolo[34-b]pyridin-5-one

SMILES

O=C(CC(c(nccc1)c1C1=O)N1c1ccccc1)N(CC1)CCN1C1CCCCC1

InChI

InChI=1S/C25H30N4O2/c30-23(28-16-14-27(15-17-28)19-8-3-1-4-9-19)18-22-24-21(12-7-13-26-24)25(31)29(22)20-10-5-2-6-11-20/h2,5-7,10-13,19,22H,1,3-4,8-9,14-18H2/t22-/m1/s1

InChI Key

HZANBXOVZBZEFZ-JOCHJYFZSA-N

MDL Number (MFCD)

MFCD27570130

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

418.54

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.931

Distribution Coefficient, logD

2.633

Water Solubility, LogSw

-3.40

Polar Surface Area

44.753

Acid Dissociation Constant (pKa)

21.17

Base Dissociation Constant (pKb)

7.40

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

48.00

P244-0156 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS BBB Library (22607 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with P244-0156 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P244-0156?
Check Price and Availability of P244-0156, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P244-0156 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P244-0156
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P244-0156
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P244-0156 available by request