P257-1163 Screening compound: 4-(4-methylpiperazin-1-yl)-5-[4-(piperidine-1-carbonyl)piperidin-1-yl]pyrimidine

P257-1163 Screening compound: 4-(4-methylpiperazin-1-yl)-5-[4-(piperidine-1-carbonyl)piperidin-1-yl]pyrimidine
P257-1163 Screening compound: 4-(4-methylpiperazin-1-yl)-5-[4-(piperidine-1-carbonyl)piperidin-1-yl]pyrimidine alternative view

Chemical Structure Depiction of ChemDiv screening compound P257-1163
4-(4-methylpiperazin-1-yl)-5-[4-(piperidine-1-carbonyl)piperidin-1-yl]pyrimidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P257-1163

Molecular Formula

C20H32N6O (C20 H32 N6 O)

Compound Name

4-(4-methylpiperazin-1-yl)-5-[4-(piperidine-1-carbonyl)piperidin-1-yl]pyrimidine

IUPAC name

4-(4-methylpiperazin-1-yl)-5-[4-(piperidine-1-carbonyl)piperidin-1-yl]pyrimidine

SMILES

CN(CC1)CCN1c(ncnc1)c1N(CC1)CCC1C(N1CCCCC1)=O

InChI

InChI=1S/C20H32N6O/c1-23-11-13-25(14-12-23)19-18(15-21-16-22-19)24-9-5-17(6-10-24)20(27)26-7-3-2-4-8-26/h15-17H,2-14H2,1H3

InChI Key

BHGUROWWFRPYNM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27570688

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

372.51

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.594

Distribution Coefficient, logD

1.118

Water Solubility, LogSw

-1.49

Polar Surface Area

47.180

Acid Dissociation Constant (pKa)

22.82

Base Dissociation Constant (pKb)

7.70

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

75.00

P257-1163 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

CNS BBB Library (22607 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with P257-1163 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P257-1163?
Check Price and Availability of P257-1163, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P257-1163 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P257-1163
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P257-1163
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P257-1163 available by request