P271-0986 Screening compound: 8-(1-{2,3-diethylpyrido[2,3-b]pyrazin-7-yl}piperidine-4-carbonyl)-1,4-dioxa-8-azaspiro[4.5]decane

P271-0986 Screening compound: 8-(1-{2,3-diethylpyrido[2,3-b]pyrazin-7-yl}piperidine-4-carbonyl)-1,4-dioxa-8-azaspiro[4.5]decane
P271-0986 Screening compound: 8-(1-{2,3-diethylpyrido[2,3-b]pyrazin-7-yl}piperidine-4-carbonyl)-1,4-dioxa-8-azaspiro[4.5]decane alternative view

Chemical Structure Depiction of ChemDiv screening compound P271-0986
8-(1-{2,3-diethylpyrido[2,3-b]pyrazin-7-yl}piperidine-4-carbonyl)-1,4-dioxa-8-azaspiro[4.5]decane

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P271-0986

Molecular Formula

C24H33N5O3 (C24 H33 N5 O3)

Compound Name

8-(1-{2,3-diethylpyrido[2,3-b]pyrazin-7-yl}piperidine-4-carbonyl)-1,4-dioxa-8-azaspiro[4.5]decane

IUPAC name

8-(1-{23-diethylpyrido[23-b]pyrazin-7-yl}piperidine-4-carbonyl)-14-dioxa-8-azaspiro[4.5]decane

SMILES

CCc1c(CC)nc2ncc(N(CC3)CCC3C(N(CC3)CCC33OCCO3)=O)cc2n1

InChI

InChI=1S/C24H33N5O3/c1-3-19-20(4-2)27-22-21(26-19)15-18(16-25-22)28-9-5-17(6-10-28)23(30)29-11-7-24(8-12-29)31-13-14-32-24/h15-17H,3-14H2,1-2H3

InChI Key

JVZJKTKBXUICRD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27571044

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

439.56

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.370

Distribution Coefficient, logD

2.365

Water Solubility, LogSw

-2.37

Polar Surface Area

64.704

Acid Dissociation Constant (pKa)

22.83

Base Dissociation Constant (pKb)

10.17

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

66.70

P271-0986 in Drug Discovery

Included in Screening Libraries

Eccentric PPI Library (11937 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular

References: we are preparing a list of scientific research reports with P271-0986 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P271-0986?
Check Price and Availability of P271-0986, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P271-0986 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P271-0986
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P271-0986
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P271-0986 available by request