P315-0543 Screening compound: 1-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[1-(4-fluorophenyl)-2-oxopyrrolidin-3-yl]urea

P315-0543 Screening compound: 1-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[1-(4-fluorophenyl)-2-oxopyrrolidin-3-yl]urea
P315-0543 Screening compound: 1-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[1-(4-fluorophenyl)-2-oxopyrrolidin-3-yl]urea alternative view

Chemical Structure Depiction of ChemDiv screening compound P315-0543
1-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[1-(4-fluorophenyl)-2-oxopyrrolidin-3-yl]urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P315-0543

Molecular Formula

C19H18FN3O4 (C19 H18 FN3 O4)

Compound Name

1-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[1-(4-fluorophenyl)-2-oxopyrrolidin-3-yl]urea

IUPAC name

1-(23-dihydro-14-benzodioxin-6-yl)-3-[1-(4-fluorophenyl)-2-oxopyrrolidin-3-yl]urea

SMILES

O=C(NC(CCN1c(cc2)ccc2F)C1=O)Nc(cc1)cc2c1OCCO2

InChI

InChI=1S/C19H18FN3O4/c20-12-1-4-14(5-2-12)23-8-7-15(18(23)24)22-19(25)21-13-3-6-16-17(11-13)27-10-9-26-16/h1-6,11,15H,7-10H2,(H2,21,22,25)/t15-/m1/s1

InChI Key

SXNKUBHRIBJVQU-OAHLLOKOSA-N

MDL Number (MFCD)

MFCD27572048

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

371.37

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.449

Distribution Coefficient, logD

1.449

Water Solubility, LogSw

-2.13

Polar Surface Area

66.149

Acid Dissociation Constant (pKa)

11.52

Base Dissociation Constant (pKb)

2.17

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

26.30

P315-0543 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Akt-Targeted Library (14764 compounds)

Ion Channels Focused Library (26372 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Nervous system
  • Cardiovascular
Targets:
  • Others
  • Kinases
  • Ion Channels
Mechanism of action:
  • Epigenetic
Agro:
  • Agro

References: we are preparing a list of scientific research reports with P315-0543 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P315-0543?
Check Price and Availability of P315-0543, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P315-0543 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P315-0543
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P315-0543
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P315-0543 available by request