P322-0480 Screening compound: 8-{6-chloroimidazo[1,2-a]pyridine-2-carbonyl}-1,4-dioxa-8-azaspiro[4.5]decane

P322-0480 Screening compound: 8-{6-chloroimidazo[1,2-a]pyridine-2-carbonyl}-1,4-dioxa-8-azaspiro[4.5]decane
P322-0480 Screening compound: 8-{6-chloroimidazo[1,2-a]pyridine-2-carbonyl}-1,4-dioxa-8-azaspiro[4.5]decane alternative view

Chemical Structure Depiction of ChemDiv screening compound P322-0480
8-{6-chloroimidazo[1,2-a]pyridine-2-carbonyl}-1,4-dioxa-8-azaspiro[4.5]decane

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P322-0480

Molecular Formula

C15H16ClN3O3 (C15 H16 ClN3 O3)

Compound Name

8-{6-chloroimidazo[1,2-a]pyridine-2-carbonyl}-1,4-dioxa-8-azaspiro[4.5]decane

IUPAC name

8-{6-chloroimidazo[12-a]pyridine-2-carbonyl}-14-dioxa-8-azaspiro[4.5]decane

SMILES

O=C(c1cn(cc(cc2)Cl)c2n1)N(CC1)CCC11OCCO1

InChI

InChI=1S/C15H16ClN3O3/c16-11-1-2-13-17-12(10-19(13)9-11)14(20)18-5-3-15(4-6-18)21-7-8-22-15/h1-2,9-10H,3-8H2

InChI Key

WBCLSHJOMFCGNN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD12204307

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

321.76

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

1.701

Distribution Coefficient, logD

1.701

Water Solubility, LogSw

-2.36

Polar Surface Area

40.883

Acid Dissociation Constant (pKa)

27.37

Base Dissociation Constant (pKb)

2.99

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

46.70

P322-0480 in Drug Discovery

Included in Screening Libraries

CNS BBB Library (22607 compounds)

Eccentric PPI Library (11937 compounds)

GPCR Targeted Library (31838 compounds)

Protein-Protein Interaction Library (218420 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Nervous system
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • Receptor's ligands
  • PPI modulators
Structure:
  • Cyclic compounds
Targets:
  • GPCR
  • Ion Channels

References: we are preparing a list of scientific research reports with P322-0480 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P322-0480?
Check Price and Availability of P322-0480, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P322-0480 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P322-0480
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P322-0480
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P322-0480 available by request