P368-0876 Screening compound: CYCLOPROPYL[1-[(3-METHYLPIPERIDINO)CARBONYL]-3,4-DIHYDRO-2(1H)-ISOQUINOLINYL]METHANONE

P368-0876 Screening compound: CYCLOPROPYL[1-[(3-METHYLPIPERIDINO)CARBONYL]-3,4-DIHYDRO-2(1H)-ISOQUINOLINYL]METHANONE
P368-0876 Screening compound: CYCLOPROPYL[1-[(3-METHYLPIPERIDINO)CARBONYL]-3,4-DIHYDRO-2(1H)-ISOQUINOLINYL]METHANONE alternative view

Chemical Structure Depiction of ChemDiv screening compound P368-0876
CYCLOPROPYL[1-[(3-METHYLPIPERIDINO)CARBONYL]-3,4-DIHYDRO-2(1H)-ISOQUINOLINYL]METHANONE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P368-0876

Molecular Formula

C20H26N2O2 (C20 H26 N2 O2)

Compound Name

CYCLOPROPYL[1-[(3-METHYLPIPERIDINO)CARBONYL]-3,4-DIHYDRO-2(1H)-ISOQUINOLINYL]METHANONE

IUPAC name

n/a

SMILES

CC(CCC1)CN1C(C(c1c(CC2)cccc1)N2C(C1CC1)=O)=O

InChI

InChI=1S/C20H26N2O2/c1-14-5-4-11-21(13-14)20(24)18-17-7-3-2-6-15(17)10-12-22(18)19(23)16-8-9-16/h2-3,6-7,14,16,18H,4-5,8-13H2,1H3

InChI Key

VQCPLDINWXVYBL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27573939

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

326.44

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.201

Distribution Coefficient, logD

3.201

Water Solubility, LogSw

-3.33

Polar Surface Area

33.238

Acid Dissociation Constant (pKa)

19.37

Base Dissociation Constant (pKb)

3.64

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

60.00

P368-0876 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Soluble Diversity Library (15920 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with P368-0876 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P368-0876?
Check Price and Availability of P368-0876, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P368-0876 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P368-0876
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P368-0876
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P368-0876 available by request